Results 41 to 50 of about 15,716,870 (262)
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Effect of temperature on Apis indica workers
Recent work on the effect of environmental temperature on the European honeybee, Apis mellifera 1–3, has been partially repeated with two colonies of Apis indica brought from Ceylon by Mr. L. A. S. Perera.
Free, J. B. +2 more
core +1 more source
Surfactant and temperature effects on paraben transport through silicone membranes [PDF]
This study investigates the effects of two surfactants (one anionic and one non-ionic) and controlled modifications in temperature (298–323 K) on the permeation of two structurally similar compounds through a silicone membrane using a Franz diffusion ...
Bibi, Aisha +4 more
core +1 more source
The effect of low temperature on the Raman spectra of calcium-rich sulfates on Mars [PDF]
Raman spectra (532 nm diode laser) of gypsum, syngenite and görgeyite powders were studied from 273 to 83 K every −10 K. Although it was found that not all the Raman peaks are temperature-sensitive, the effect of temperature on the Raman signal of some ...
Juan Manuel Madariaga +9 more
core +1 more source
Ionic liquids (ILs) have been widely used for lignocellulose fractionation and lignin isolation. However, the effect of IL treatment on lignin structure has been less explored.
Eun-Ah Lee +11 more
doaj
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Temperature effect on elastic modulus of thin films and nanocrystals
The stability of nanoscale devices is directly related to elasticity and the effect of temperature on the elasticity of thin films and nanocrystals. The elastic instability induced by rising temperature will cause the failure of integrated circuits and ...
秦福麒 +4 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source

