Results 141 to 150 of about 18,906,331 (342)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Spatiotemporal Analysis of Ventilation Efficiency in Single-Span Plastic Greenhouses in Hot-Humid Regions of China: Using Validated CFD Modeling

open access: yesAgriculture
To characterize the spatiotemporal distribution of temperature and airflow in single-span plastic-film greenhouses, we coupled field experiments with three-dimensional computational fluid dynamics (CFD) simulations in a warm–temperate region of China ...
Song Wang   +12 more
doaj   +1 more source

Prediction of Thermal Behavior of Pervious Concrete Pavements in Winter [PDF]

open access: yes, 2017
Because application of pervious concrete pavement (PCPs) has extended to cold-climate regions of the United States, the safety and mobility of PCP installations during the winter season need to be maintained.
Chen, Zhao   +3 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

DEVELOPMENT OF HEATED STREAM ABOVE THE HORIZONTAL SURFACE

open access: yesИзвестия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2014
The development of thermal contaminated air stream formed above the surface of lengthy heated plate is investigated on the basis of the mathematical model of heat and mass transfer processes.
P. I. Diachek   +2 more
doaj  

Hybrid Prediction Model of the Temperature Field of a Motorized Spindle

open access: yes, 2017
The thermal characteristics of a motorized spindle are the main determinants of its performance, and influence the machining accuracy of computer numerical control machine tools.
Lixiu Zhang   +4 more
semanticscholar   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

Two-Dimensional Temperature Field Distribution Reconstruction Based on Least Square Method and Radial Basis Function Approximation

open access: yes, 2017
The information of temperature field distribution is complex but quite important for theoretical study and industrial applications, such as burning, drying, and heating, because it can reflect the internal running state of industrial equipment, assist to
Ruixi Jia, Qingyu Xiong
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy