Results 41 to 50 of about 1,793,986 (298)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Tangling clustering of inertial particles in stably stratified turbulence
, 2010 We have predicted theoretically and detected in laboratory experiments a new type of particle clustering (tangling clustering of inertial particles) in a stably stratified turbulence with imposed mean vertical temperature gradient.
A. Eidelman +15 more
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Pressure-gradient-induced Alfven eigenmodes: II. Kinetic excitation with ion temperature gradient
, 2009 The kinetic excitation of ideal magnetohydrodynamic (MHD) discrete Alfven eigenmodes in the second MHD ballooning stable domain is studied in the presence of a thermal ion temperature gradient (ITG), using linear gyrokinetic particle-in-cell simulations ...
Bierwage, Andreas +2 more
core +1 more source
Magnonic analog of the Edelstein effect in antiferromagnetic insulators [PDF]
, 2020 We investigate the nonequilibrium spin polarization due to a temperature gradient in antiferromagnetic insulators, which is the magnonic analog of the inverse spin-galvanic effect of electrons. We derive a linear-response theory of a temperature-gradient-
Kovalev, Alexey +3 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Thermal Bowing of Reinforced Concrete Elements Exposed to Non-Uniform Heating
Archives of Civil Engineering, 2018 The paper presents the test description and results of thermal bowing of RC beams exposed to non-uniform heating at high temperature. Bending of a non-uniformly heated element is caused by free thermal elongation of the material it is made of. The higher
Kowalski R. +2 more
doaj +1 more source
Horizontal Distribution of Temperature Effect in Rubberized Concrete Pavement: A Case Study
Buildings, 2023 Temperature distribution and the deformation behavior under temperature are important parameters in the design and evaluation of concrete pavements. In this paper, in order to study the horizontal distribution of the temperature effect on rubberized ...
Gaowang Zhang +3 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source