Results 41 to 50 of about 5,330,759 (310)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Eocene temperature gradients [PDF]
Nature Geoscience, 2017 [no abstract]
Tierney, Jessica E +4 more
openaire +5 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Thermal Bowing of Reinforced Concrete Elements Exposed to Non-Uniform Heating
Archives of Civil Engineering, 2018 The paper presents the test description and results of thermal bowing of RC beams exposed to non-uniform heating at high temperature. Bending of a non-uniformly heated element is caused by free thermal elongation of the material it is made of. The higher
Kowalski R. +2 more
doaj +1 more source
Identification of Thermally-Tagged Coherent Structures in the Zero Pressure Gradient Turbulent Boundary Layer [PDF]
, 2013 A zero pressure gradient boundary layer over a flat plate is subjected to step changes in thermal condition at the wall, causing the formation of internal, heated layers.
Rought, Rebecca Lynn
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
, 2014 Experimental and simulated results of voltage-temperature gradient (a) and current-temperature gradient (b) behavior of the cells.
Sher Bahadar Khan (508662) +7 more
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Effect of XLPE/EPDM Interface on Space Charge Behavior in Cable Accessory
IEEE Access, 2019 Space charges accumulate easily at insulation interface of cable accessories, which cause different electric field distribution and aging characteristics compared to single-layered cable.
Mingxiao Zhu +5 more
doaj +1 more source
Temperature gradient analysis.
, 2013 Temperature gradient analysis of the primers with A. fumigatus DNA template. Analysis performed using SYBR Green.
Stephen A. Bustin (316436) +4 more
core +1 more source