Results 91 to 100 of about 9,537,873 (210)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Colorimetric Temperature Measurement Method Considering Influence of Ambient Temperature
Colorimetric temperature measurement has important applications in industrial production. However, it’s usually applied to high temperature measurement because it lacks accuracy in medium-low temperature measurement.
Zheng Bin, Ding Guoqing
doaj +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Influence and Interaction of Temperature, H2S and pH on Concrete Sewer Pipe Corrosion [PDF]
Concrete sewer pipes are known to suffer from a process of hydrogen sulfide gas induced sulfuric acid corrosion. This leads to premature pipe degradation, performance failure and collapses which in turn may lead to property and health damage.
Mahmoodian, Mojtaba +2 more
core
Influence of physiological factors on growth, sporulation and ochratoxin A/B production of the new Aspergillus ochraceus grouping [PDF]
Recently, new species within the Aspergillus section Circumdati group responsible for ochratoxin production were reported. This study has examined the impact of interactions between water activity (aw, 0.99-0.90), temperature (20-35 °C) on growth ...
N. Magan +3 more
core +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Investigating crack growth in sheet metal originating from clinched joints is a major part of predicting the service life of mechanically joined structures. Clinching allows different materials to be joined together.
Gunter Kullmer +4 more
doaj +1 more source
Contact loss between railway track and subgrade in vertical plane during roadbed research
In the paper a new method of railway subgrade investigation is analysed. Contact loss between track and subgrade in vertical plane is considered. During the roadbed investigations the rail is jacked up using a plate called „VSSâ€.
Wołodzimierz Bednarek +1 more
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Vibrating plates have been recently used for a number of active noise control applications. They are resistant to difficult environmental conditions including dust, humidity, and even precipitation.
Krzysztof MAZUR, Marek PAWEŁCZYK
doaj

