Results 61 to 70 of about 260,402 (260)
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Glass Ceramic Fibers Containing PbS Quantum Dots for Fluorescent Temperature Sensing
Glass ceramics (GCs) containing PbS quantum dots (QDs) are prepared for temperature sensing. Broadband emissions are detected in the GCs when PbS QDs are precipitated from the glasses, and emissions centers are modulated from 1250 nm to 1960 nm via heat ...
Tingyu Zha +7 more
doaj +1 more source
Temperature sensing across species [PDF]
The ability to detect changes in temperature is a fundamental sensory mechanism for every species and provides organisms with a detailed view of the environment. This review focuses on what is known of the neuronal and molecular substrates for thermosensation across species, focusing on the three robust model systems extensively used to study sensory ...
openaire +2 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Spectral-Based Temperature Sensing in Cr:LiCAF Crystals Using Fluorescence Peak Shift Calibration
In this study, we present a non-invasive and contactless method for estimating the internal temperature of Cr:LiCAF laser crystals using temperature-dependent shifts in fluorescence emission peaks.
Yusuf Öztürk
doaj +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Mode-Enhanced Surface Plasmon Resonance in Few-Mode Fibers via Dual-Groove Architecture
We propose a dual-groove few-mode fiber surface plasmon resonance sensor that exploits the LP11 mode for enhanced plasmonic sensing. The device incorporates two physically separated grooves with distinct metallic coatings, enabling dual-channel operation
Qin Wu +4 more
doaj +1 more source
Multi-Task Learning for Multi-Dimensional Regression: Application to Luminescence Sensing
The classical approach to non-linear regression in physics is to take a mathematical model describing the functional dependence of the dependent variable from a set of independent variables, and then using non-linear fitting algorithms, extract the ...
Umberto Michelucci, Francesca Venturini
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Temperature sensing property of microdisk resonator
The transmission equation of microdisk resonator is obtained by the transfer matrix method. The physical model is built and the electric field distribution, output spectrum and phase of the microdisk resonator are simulated by three-dimensional finite ...
LIU Chun-juan +3 more
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