Results 71 to 80 of about 4,794,388 (242)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Investigation into the use of satellite remote sensing data products as part of a multi-modal marine environmental monitoring network [PDF]

open access: yes, 2012
In this paper it is investigated how conventional in-situ sensor networks can be complemented by the satellite data streams available through numerous platforms orbiting the earth and the combined analyses products available through services such as ...
O\u27Connor, Edel   +9 more
core   +3 more sources

Temperature sensing property of microdisk resonator

open access: yesJournal of Measurement Science and Instrumentation, 2020
The transmission equation of microdisk resonator is obtained by the transfer matrix method. The physical model is built and the electric field distribution, output spectrum and phase of the microdisk resonator are simulated by three-dimensional finite ...
LIU Chun-juan   +3 more
doaj  

Multi-Task Learning for Multi-Dimensional Regression: Application to Luminescence Sensing

open access: yesApplied Sciences, 2019
The classical approach to non-linear regression in physics is to take a mathematical model describing the functional dependence of the dependent variable from a set of independent variables, and then using non-linear fitting algorithms, extract the ...
Umberto Michelucci, Francesca Venturini
doaj   +1 more source

Photonic crystal fiber half-taper probe based refractometer [PDF]

open access: yes, 2014
A compact singlemode - photonic crystal fiber - singlemode fiber tip (SPST) refractive index sensor is demonstrated in this paper. A CO2 laser cleaving technique is utilised to provide a clean-cut fiber tip which is then coated by a layer of gold to ...
Bo, Lin   +8 more
core   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

‘Staying Hot’: Investigating the influence of overnight conditions on the penile skin temperature during male sexual arousal—A novel methodology for nocturnal erection detection

open access: yesBJUI Compass
Objective The objective of this study is to assess the impact of overnight environmental conditions on erectile penile temperature within a controlled setting, with the aim of investigating the feasibility of using temperature measurements for nocturnal ...
Hille J. Torenvlied   +4 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Distributed optical fibre sensing at 1.65µm using a Q-switched fibre laser

open access: yes
It is becoming increasingly vital to monitor telecommunication links during operation and installation process. By using a high peak power source and the optical time domain reflectometry (OTDR) technique operating at the wavelength region of 1.6µm, it ...
Newson, T.P., Kee, H.H., Lees, G.P.
core   +1 more source

Tunable luminescence and ratiometric temperature sensing by hierarchical self-assembly of lanthanide-organic cage

open access: yesNano Research
Luminescent materials with tunable emission wavelengths/colors hold great potential for smart response devices, data security, sensors, and so on. However, development of stimuli-responsive luminescent materials with traditional organic or inorganic ...
Xuan Deng   +6 more
doaj   +1 more source

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