Results 71 to 80 of about 4,794,388 (242)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Investigation into the use of satellite remote sensing data products as part of a multi-modal marine environmental monitoring network [PDF]
In this paper it is investigated how conventional in-situ sensor networks can be complemented by the satellite data streams available through numerous platforms orbiting the earth and the combined analyses products available through services such as ...
O\u27Connor, Edel +9 more
core +3 more sources
Temperature sensing property of microdisk resonator
The transmission equation of microdisk resonator is obtained by the transfer matrix method. The physical model is built and the electric field distribution, output spectrum and phase of the microdisk resonator are simulated by three-dimensional finite ...
LIU Chun-juan +3 more
doaj
Multi-Task Learning for Multi-Dimensional Regression: Application to Luminescence Sensing
The classical approach to non-linear regression in physics is to take a mathematical model describing the functional dependence of the dependent variable from a set of independent variables, and then using non-linear fitting algorithms, extract the ...
Umberto Michelucci, Francesca Venturini
doaj +1 more source
Photonic crystal fiber half-taper probe based refractometer [PDF]
A compact singlemode - photonic crystal fiber - singlemode fiber tip (SPST) refractive index sensor is demonstrated in this paper. A CO2 laser cleaving technique is utilised to provide a clean-cut fiber tip which is then coated by a layer of gold to ...
Bo, Lin +8 more
core +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Objective The objective of this study is to assess the impact of overnight environmental conditions on erectile penile temperature within a controlled setting, with the aim of investigating the feasibility of using temperature measurements for nocturnal ...
Hille J. Torenvlied +4 more
doaj +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Distributed optical fibre sensing at 1.65µm using a Q-switched fibre laser
It is becoming increasingly vital to monitor telecommunication links during operation and installation process. By using a high peak power source and the optical time domain reflectometry (OTDR) technique operating at the wavelength region of 1.6µm, it ...
Newson, T.P., Kee, H.H., Lees, G.P.
core +1 more source
Luminescent materials with tunable emission wavelengths/colors hold great potential for smart response devices, data security, sensors, and so on. However, development of stimuli-responsive luminescent materials with traditional organic or inorganic ...
Xuan Deng +6 more
doaj +1 more source

