Results 141 to 150 of about 1,206,514 (314)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Storage and Temperature Stability of Emulsified Biodiesel-Diesel Blends. [PDF]

ACS Omega, 2022
Maji NC, Rastogi P, Krishnasamy A, Aidhen IS, Kaisare NS, Basavaraj MG.   +5 more
europepmc   +1 more source

A self-amplifying RNA vaccine against COVID-19 with long-term room-temperature stability. [PDF]

NPJ Vaccines, 2022
Voigt EA, Gerhardt A, Hanson D, Jennewein MF, Battisti P, Reed S, Singh J, Mohamath R, Bakken J, Beaver S, Press C, Soon-Shiong P, Paddon CJ, Fox CB, Casper C.   +14 more
europepmc   +2 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Development of EB-PVD TBC'S : the role of deposition temperature and plasma assistance

, 1995
Gas turbine manufacturers have achieved continuingly improved engine efficiency and thrust-to-weight ratio by designing with increased Turbine Entry Temperature (TET).
Jaslier, Yann
core  

Temperature stability.

, 2015
Purified PlicB in 20mM Tris-HCl pH 7 was incubated 10 min at different temperatures (30–60°C). Temperature stability is presented as T50 value (dashed box).
Laura I. de Eugenio (727790), Jorge Barriuso (167599), Maria J. Martínez (727791), Maria E. Vaquero (727789)   +3 more
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Improvement of the stability of hydrogenated amorphous silicon films by intermittent illumination treatment at elevated temperature

, 1996
The intermittent illumination treatment by white light at elevated temperature is proved to be a convenient and efficient method for the improvement of the stability of hydrogenated amorphous silicon (a-Si:H) films.
Kong GL, Sheng SR, Sheng SR CHINESE ACAD SCIINST SEMICONDBEIJING 100083PEOPLES R CHINA., Liao XB   +3 more
core  

Wide-Temperature-Range Stability of a Compact LNOI Hybrid Plasmonic TE-Pass Polarizer for Fiber-Optic Gyroscope Applications

Photonics
In this study, we present a thermal-aware design of a compact hybrid plasmonic grating (HPG) TE-pass polarizer on X-cut lithium niobate on insulator (LNOI) for fiber-optic gyroscopes (FOGs).
Hanyi Zhang, Rong Fan, Yinzhou Zhi, Lulu Fang, Wenxuan Cheng, Yujie Wang, Jianfeng Bao, Lijing Li   +7 more
doaj   +1 more source

Effect of Temperature on Stability of Lipid Microbubbles

Journal of the Turkish Chemical Society Section A: Chemistry, 2019
The effect of temperature on stability of lipid microbubble shell containing polyethyleneoxide-40-stearate (PEG40St) as emulsifier was investigated. Microbubbles at 4 °C were subjected to different temperatures up to 48 ºC (down-to-up) and it was found that both the number and the size of microbubbles remained unchanged in the population up to a ...
openaire   +4 more sources