Results 51 to 60 of about 692,010 (217)
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Does hut climate matter for piglet survival in organic production?
Animal, 2019 Piglet mortality in outdoor production systems varies across the year, and a reason for this variation could be fluctuations in hut climate, as ambient temperature might influence piglet survival, both directly and indirectly.
S.-L.A. Schild +4 more
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Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Seasonal and diel variation in body temperature and heart rate of the Eurasian beaver
Animal BiotelemetryKnowledge concerning diel and seasonal variation of body temperature and metabolic rates can provide useful information concerning the physiology, ecology, and behavior of animals and how they are adapted to living in cold conditions.
Martin Mayer +5 more
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Soil Respiration Characteristics and Influencing Factors of Shrub Ecosystem on the Loess Plateau
Renmin Zhujiang, 2022 Soil respiration is one of the main sources of atmospheric carbon.In recent years,the vegetation cover of the Loess Plateau has changed significantly.To explore the change rules and influencing factors of soil respiration in the shrub ecosystem,this ...
ZHANG Kuiyue +6 more
doaj
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Temperature Sensitivity as a Microbial Trait Using Parameters from Macromolecular Rate Theory
Frontiers in Microbiology, 2016 The activity of soil microbial extracellular enzymes is strongly controlled by temperature, yet the degree to which temperature sensitivity varies by microbe and enzyme type is unclear.
Charlotte Jean Alster +9 more
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Exact solution for thermal boundary layer in Casson fluid flow over permeable shrinking sheet with
Alexandria Engineering Journal, 2016 An analysis of thermal boundary layer in the flow of Casson fluid over a permeable shrinking sheet with variable wall temperature and thermal radiation is made. Using similarity transformations, self-similar nonlinear ODEs are obtained from the governing
Krishnendu Bhattacharyya +2 more
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