Results 121 to 130 of about 2,039,832 (291)

Free convection boundary layers driven by exothermic surface reactions: critical ambient temperatures [PDF]

, 1995
A model for the free convection boundary-layer flow near a forward stagnation point driven by heating from a surface on which there is a catalytic reaction is discussed.
Liñán Martínez, Amable, Chaudhary, M.A., Merkin, J.H.   +2 more
core  

Temperature dependence of temperature sensitive luminophores at cryogenic temperatures

The Proceedings of the International Conference on Power Engineering (ICOPE), 2021
LI, Yanrong, SOMEYA, Satoshi, YASUZAWA, Sou, INAGAKI, Terumi, SAITO, Shimpei, BABA, Soumei, TAKADA, Naoki   +6 more
openaire   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Synthesis of Nanoparticles of Different Morphology in a DC Discharge

Nanomaterials
The synthesis of nanoparticles in the plasma of a stratified DC gas discharge was carried out under typical gas discharge conditions, i.e., at room temperature and an argon pressure of 0.11 torr, with a discharge current of 2.5 mA.
Alexander V. Fedoseev, Anatoly V. Filippov, Mikhail M. Vasiliev, Oleg F. Petrov   +3 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

North Atlantic Ocean temperatures way above normal (October 2010): part 1

, 2016
Analysis by the NOAA Climate Prediction Center reveals that sea surface temperatures in the North Atlantic near Greenland are well above normal levels. The above average temperatures can be seen in the image shown here, as a large area of red surrounding
National Oceanic and Atmospheric Administration
core   +2 more sources

Corrigendum: Ontologies and databases on thermophysical properties of nuclear reactor materials (NUCET 5(2): pp. 145–153, 2019) [PDF]

Nuclear Energy and Technology, 2023
Igor Chusov, Pavel Kirillov, Vladimir Pronyaev, Adilbek Erkimbaev, Vladimir Zitserman, Georgy Kobzev, Lev Fokin   +6 more
doaj   +3 more sources