Results 101 to 110 of about 3,634,731 (300)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Quantum Simulators at Negative Absolute Temperatures
, 2012 We propose that negative absolute temperatures in ultracold atomic clouds in optical lattices can be used to simulate quantum systems in new regions of phase diagrams.
Rapp, Akos
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Three Flavor QCD at High Temperatures
, 2004 We have continued our study of the phase diagram of high temperature QCD with three flavors of improved staggered quarks. We are performing simulations with three degenerate quarks with masses less than or equal to the strange quark mass m_s and with ...
Bernard +19 more
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
New Journal of Physics, 2013 A mathematical simulation of a dust particle's behavior in the electrodynamic linear quadrupole trap with closing end electrodes allowed us to reveal several features of the phenomena.
L M Vasilyak +7 more
doaj +1 more source
Martian surface temperatures [PDF]
Reduction of infrared scan data on Martian surface ...
Morrison, D.
core +1 more source
Adhesive for aluminum withstands cryogenic temperatures [PDF]
, 1972 Polyurethane adhesive mixed to various proportions with milled glass fibers match the thermal characteristics of 2014-T6 aluminum at cryogenic ...
Helf, J. C., Hill, W. L., Matsuoka, T.
core +1 more source