Results 91 to 100 of about 3,634,731 (300)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Characteristic temperatures of exchange biased systems
, 2006 Characteristic temperatures in ferromagnetic - antiferromagnetic exchange biased systems are analyzed. In addition to usual blocking temperature of exchange bias $T_{B}$, and the N\'{e}el temperature of an antiferromagnet $T_{N}$, the inducing ...
Dobrynin, Alexey N., Prozorov, Ruslan
core +1 more source
Temperature-Sombor and Temperature-Nirmala Indices
INTERNATIONAL JOURNAL OF MATHEMATICS AND COMPUTER RESEARCH, 2022 In this paper, we introduce the temperature-Sombor index, modified temperature-Sombor index and temperature-Nirmala index of a graph. Also we compute these temperature indices for some standard graphs and tetrameric 1,3-adamantane. Furthermore, we establish some properties of newly defined temperature-Sombor index and temperature-Nirmala index.
openaire +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Magnetism in SQUIDs at Millikelvin Temperatures
, 2008 We have characterized the temperature dependence of the flux threading dc SQUIDs cooled to millikelvin temperatures. The flux increases as 1/T as temperature is lowered; moreover, the flux change is proportional to the density of trapped vortices.
A. Kittel +7 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
AtomsIn the present work, the influence of external X-ray radiation on the kinetics of multicharged ions in high-temperature plasma is investigated. A generalized diagnostic approach is proposed for the electron density and temperature measurements of photo ...
Roman K. Kulikov +2 more
doaj +1 more source
On lunar ''temperatures'' [PDF]
Thermal measurements on lunar surface at radio ...
Hopfield, J. J.
core +1 more source
Shock and Release Temperatures in Molybdenum
, 2007 Shock and release temperatures in Mo were calculated, taking account of heating from plastic flow predicted using the Steinberg-Guinan model. Plastic flow was calculated self-consistently with the shock jump conditions: this is necessary for a rigorous ...
A. Seifter +10 more
core +1 more source