Results 141 to 150 of about 15,995 (290)

Educação em tempo integral : ampliando as possibilidades educacionais [PDF]

open access: yes, 2014
Orientador : Prof. Ms. Mariana F. TaquesMonografia (especialização) - Universidade Federal do Paraná, Setor de Educação, Curso de Especialização em Coordenação PedagógicaInclui referênciasResumo : O tema do presente trabalho é estudar os saberes e ...
Silva, Ivene Regina da
core  

Cobalt/Photoredox Catalyzed Desymmetrization of Oxo and Azabicycles via Asymmetric Reductive Coupling With Alkynes

open access: yesAdvanced Science, EarlyView.
A one‐step, asymmetric reductive coupling of alkynes and oxa‐ and aza‐bicyclic olefins using a cobalt/photoredox catalytic system through desymmetrization. ABSTRACT Bicyclo[2.2.1]heptane frameworks represent a privileged structural motif prevalent in numerous natural products and bioactive molecules.
Subhankar Pradhan   +5 more
wiley   +1 more source

Educação em tempo integral: direito e financiamento

open access: yes, 2012
O artigo tem por objetivo analisar e os desafios associados ao financiamento da educação em tempo integral. Parte-se da análise dos mo(vi)mentos legais relacionados à Educação Integral (em tempo) integral ...
Menezes, Janaína S.S.
core  

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

open access: yesAdvanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan   +24 more
wiley   +1 more source

An Implantable Optogenetics‐Engineered Hydrogel for Amelioration of Rheumatoid Arthritis through Light‐Controlled Metabolic Reprogramming of Synovial Macrophages

open access: yesAdvanced Science, EarlyView.
An implantable hydrogel is designed to enable in situ and on‐demand secretion of GLP‐1 in synovium through blue light irradiation to activate GLP‐1R/HK2/VDAC1 pathway for upregulating tricarboxylic acid cycle and oxidative phosphorylation in macrophage, facilitating tissue repair and bone erosion recovery.
Dahai Hu   +10 more
wiley   +1 more source

O QUE É INTEGRAL: a educação ou o tempo?

open access: yes, 2019
Este artigo apresenta uma pesquisa realizada em uma escola de tempo integral da rede estadual do Estado do Tocantins. Ele objetiva analisar se a educação ofertada pela escola pesquisada é Educação Integral ou apenas de Tempo Integral.
Oliveira, Ana Claudia Martins de   +1 more
core  

Crystal Facet‐Polysaccharide Matching in CFS‐P Nanocrystals Drives Fungal Uptake, Vacuole Destruction, and Selective Antifungal Activity

open access: yesAdvanced Science, EarlyView.
Facet‐engineered PVP‐capped CuFeSe2 nanocrystals exhibit potent, selective antifungal activity by strongly binding cell‐wall mannan, enabling vacuolar entry and organelle disruption. High‐index facets show superior mannan affinity, validated by theoretical calculations and experiments. CFS‐P induces vacuolar cavitation, mitochondrial abnormalities, and
Zhaohui Wang   +10 more
wiley   +1 more source

Tempo Integral

open access: yesRevista do Serviço Público, 2017
openaire   +2 more sources

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao   +3 more
wiley   +1 more source

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