Results 111 to 120 of about 6,450,793 (333)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Ontología compartida, una mirada desde las redes de aprendizaje, estado del arte

open access: yesCiencia, Docencia y Tecnología, 2015
Este artículo muestra los resultados de un ejercicio de revisión de investigaciones que dan la base referencial al concepto de ontología compartida desde cuatro perspectivas: 1.
Olga Lucia Londoño   +4 more
doaj  

Spatial and Temporal Variation of Dissolved Inorganic Radiocarbon in the East Sea [PDF]

open access: diamond, 2014
Bo-Ram Sim   +3 more
openalex   +1 more source

Temporal Graph Traversals: Definitions, Algorithms, and Applications [PDF]

open access: yes, 2014
A temporal graph is a graph in which connections between vertices are active at specific times, and such temporal information leads to completely new patterns and knowledge that are not present in a non-temporal graph.
Cheng, James, Huang, Silu, Wu, Huanhuan
core  

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Study on Spatial Distribution Dispersion Evaluation and Driving Forces of Rural Settlements in the Yellow River Basin

open access: yesLand
The spatial distribution pattern of rural settlements in the Yellow River Basin is scattered and numerous. It is of great significance to study the discrete distribution of rural settlements for achieving high-quality development and promoting rural ...
Heying Li   +6 more
doaj   +1 more source

Intrinsic Temporal Regularization for High-resolution Human Video Synthesis [PDF]

open access: green, 2020
Lingbo Yang   +4 more
openalex   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

open access: yesAging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst   +4 more
wiley   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao   +10 more
wiley   +1 more source

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