Results 121 to 130 of about 67,116 (306)

A Dual‐Phase Exosomal Nanotherapy Enhances Continual Efferocytosis by Coordinating Checkpoint Inhibition and Metabolic Reprogramming in Atherosclerosis

Advanced Science, EarlyView.
Here we developed Am@SExo, a dual‐functional engineered exosome that coordinates CD47–SIRPα checkpoint blockade with Arg1 mRNA–mediated metabolic reprogramming. Surface SIRPα promotes recognition of apoptotic cells and plaque targeting, while Arg1 expression enhances arginine–ornithine metabolism, Rac1 activation, and actin remodeling in macrophages ...
Danwen Zheng, Shiteng Cai, Jinfeng Gao, Sheng Zhao, Bohan Wei, Xueyi Weng, Zhengmin Wang, Qiaozi Wang, Qiyu Li, Chengzhi Han, Weiyan Li, Yiwen Tan, Yuyuan Fu, Meng Ji, Zheyong Huang, Yanan Song, Juying Qian, Junbo Ge   +17 more
wiley   +1 more source

BIBN4096BS and CGRP(8-37) antagonize the relaxant effects of alpha-CGRP more than those of beta-CGRP in human extracranial arteries

, 2005
We hypothesize that dilatation of extracranial arteries during migraine could be caused by CGRP. We compared the relaxant effects of alpha-calcitonin gene-related peptide (alpha-CGRP) and beta-calcitonin gene-related peptide (beta-CGRP) and the ...
Hoffmann, S., Webel, Martin, Kaumann, Alberto J., Wojtas, K., Verheggen, Raphaela   +4 more
core   +1 more source

Generation of Self‐Organizing Macrovascular Constructs by Bioprinting Human iPSC‐Derived Mesodermal Progenitor Cells

Advanced Science, EarlyView.
ABSTRACT Vascularization remains a major obstacle in tissue engineering. Here, we introduce a bioprinting strategy to generate centimeter‐scale, self‐organizing “mother vessel” constructs from iPSC‐derived hiMPCs. By optimizing bioink composition, printing was accomplished in a single‐step approach. Within one week, hiMPCs differentiated into both CD31+
Leyla E. Dogan, Nathaly A. Chicaiza‐Cabezas, Florian Kleefeldt, Philipp Wörsdörfer, Jürgen Groll, Süleyman Ergün   +5 more
wiley   +1 more source

Telencephalon vascularity in sheep (Ovis aries)

Pesquisa Veterinária Brasileira
: The studies into the vascularity of the telencephalon in Polish Merino sheep of both sexes were made on 60 cerebral hemispheres. It was found that the middle cerebral artery is the most powerful vessel supplying blood to the telencephalon.
Benedykt Skoczylas, Witold Brudnicki, Krzysztof Kirkiłło-Stacewicz, Włodzimierz Nowicki, Jan Wach   +4 more
doaj   +1 more source

Local Spasm in Cerebral Arteries.

, 1956
This work began as a clinical analysis of patients who suffered unexplained hemipareses following temporal lobectomies. A preliminary survey suggested that the site of disturbance was the internal capsule and that the cause was vascular interference ...
Lende, Richard Allan.
core  

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Biopsy of the Temporal Artery [PDF]

Mayo Clinic Proceedings, 1985
openaire   +2 more sources

Tomographic ultrasound for three-dimensional visualization of temporal arteries [Elektronisk resurs]

Objective Conventional two-dimensional ultrasound has been assessed for the non-invasive diagnosis of giant cell arteritis (GCA), but the results are operator dependent, resulting in low sensitivity.
Dahlstrand, U,, Naumovska, M,, Sheikh, R,, Merdasa, A,, Cinthio, M,, Albinsson, J,, Lund University., Malmsjo, M,, Engqvist, L,   +8 more
core   +1 more source

SOST expression is restricted to the great arteries during embryonic and neonatal cardiovascular development

, 2007
Spatial-temporal regulation of bone morphogenetic protein (BMP) and Wnt activity is essential for normal cardiovascular development, and altered activity of these growth factors causes maldevelopment of the cardiac outflow tract and great arteries.
Socrates E. Papapoulos, Conny J. van Munsteren, Michel Aguet, van der Wee-Pals, Lianne, Nathalie Vilain, Aguet, Michel, Christine L. Mummery, Rui M. Monteiro, Vilain, Nathalie, Pancras C.W. Hogendoorn, Clemens W.G.M. Löwik, van Munsteren, Conny J, Papapoulos, Socrates E., Hogendoorn, Paneras C.W., Monteiro, Rui M., Löwik, Clemens W.G.M., Peter Ten Dijke, Mummery, Christine L., Deruiter, Marco C., Ten Dijke, Peter, Hogendoorn, Pancras C. W., Van Bezooijen, Rutger L., Van Munsteren, Conny J., Marco C. DeRuiter, Visser, Annemieke, Annemieke Visser, Lianne van der Wee‐Pals, van Bezooijen, Rutger L, Löwik, Clemens W. G. M., Monteiro, Rui M.; id_orcid, Rutger L. van Bezooijen   +30 more
core   +1 more source

Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation

Advanced Science, EarlyView.
Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao, Zhengquan Wang, Hui Yang, Xiyuan Zhang, Hanyuan Liu, Xiaotong Lu, Xiaocheng Li, Yanyan Liu, Xi Zhao, Wenhao Zhou, Yufeng Zheng   +10 more
wiley   +1 more source