Results 111 to 120 of about 16,573 (218)

The Adequate Number of Histopathology Cross-sections of Temporal Artery Biopsy in Establishing the Diagnosis of Giant Cell Arteritis. [PDF]

J Ophthalmic Vis Res, 2021
Navahi RA, Chaibakhsh S, Alemzadeh SA, Aghdam KA.   +3 more
europepmc   +1 more source

Inflammatory Stewardship—A Perspective for Active Management of Acute Inflammation

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Inflammatory stewardship frames inflammation as a manageable clinical domain requiring explicit strategy, governance, and feedback. It aligns diagnostics, risk stratification, biomarker interpretation, and immunomodulatory decisions across perioperative and critical‐care teams.
Lennart Finn Herrlich, Hubert Schrezenmeier, David Alexander Christian Messerer   +2 more
wiley   +1 more source

Legumain Restrains Granuloma Formation by Inhibiting mTORC1/STAT1‐Mediated M1 Macrophage Polarization in Sarcoidosis

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Legumain (LGMN) is upregulated in macrophages during sarcoid‑like granuloma formation. Macrophage‑derived LGMN binds to integrin αvβ3 and suppresses mTORC1/STAT1 signaling to restrain M1 macrophage polarization. Intratracheal delivery of lipid nanoparticles carrying Lgmn plasmid DNA (pDNA) elevates LGMN expression and effectively attenuates pulmonary ...
Mengyuan Liu, Yueyin Han, Bingbing Xie, Lili Zhu, Wenxiu Xu, Yinzhen Han, Yue Liao, Shuwei Gao, Dingyuan Jiang, Jing Geng, Zhen Li, Yinan Hu, Huaping Dai   +12 more
wiley   +1 more source

A Diagnostic Challenge: From Suspected Ischemic Stroke to Confirmed Herpetic Encephalitis

Clinical Case Reports, Volume 14, Issue 6, June 2026.
Multimodal neuroimaging in a case of HSV‐1 encephalitis mimicking malignant MCA stroke: from initial CT findings misinterpreted as large territorial infarction, through decompressive craniectomy for refractory intracranial hypertension, to MRI confirmation of non‐territorial haemorrhagic encephalitis prompting CSF analysis and acyclovir therapy ...
Mafalda Dias Neves, Miguel Gonçalves Pereira, Natacha Silveira, Susana Barbosa, José Maria Matos Sousa, Eduarda Pereira, Elisabete Monteiro   +6 more
wiley   +1 more source

Multivariable prediction model for suspected giant cell arteritis: development and validation

Clinical Ophthalmology, 2017
Edsel B Ing,1 Gabriela Lahaie Luna,2 Andrew Toren,3 Royce Ing,4 John J Chen,5 Nitika Arora,6 Nurhan Torun,7 Otana A Jakpor,8 J Alexander Fraser,9 Felix J Tyndel,10 Arun NE Sundaram,10 Xinyang Liu,11 Cindy TY Lam,1 Vivek Patel,12 Ezekiel Weis,13 David ...
Ing EB, Lahaie Luna G, Toren A, Ing R, Chen JJ, Arora N, Torun N, Jakpor OA, Fraser JA, Tyndel FJ, Sundaram ANE, Liu X, Lam CTY, Patel V, Weis E, Jordan D, Gilberg S, Pagnoux C, ten Hove M   +18 more
doaj  

Meropenem‐Induced Possible Mixed Drug‐Induced Liver Injury With Cholestatic Evolution: A Case Report Evaluated Using the Updated RUCAM (2016)

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Drug‐induced liver injury (DILI) remains a diagnosis of exclusion and requires systematic causality assessment. Meropenem is generally considered hepatically safe; however, rare cases of idiosyncratic DILI have been reported. We describe a 33‐year‐old female who developed progressive elevation of liver tests following exposure to meropenem ...
Nidal Mutawodeh, Sarah Saife, Akram Shalaby, Kamaleldein Einar, Motasem Kamal, Malik Hijaz, Tariq Hamadneh   +6 more
wiley   +1 more source

Temporal artery biopsies: a fresh perspective [PDF]

ANZ Journal of Surgery, 2010
Manjuka, R, Hardman, David
openaire   +3 more sources

Methotrexate Toxicity in a Patient With Renal Failure Despite a Normal Methotrexate Concentration: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Methotrexate (MTX) is a folate antagonist widely used as a disease‐modifying antirheumatic drug (DMARD) in rheumatoid arthritis (RA), as well as in several malignancies and autoimmune disorders. Although low‐dose MTX (5–20 mg/week) is generally considered safe, it has a narrow therapeutic index, and toxicity can occur even at therapeutic doses,
Fatemeh Afra, Mahshad Ghoddusi, Mahsa Mottahedi, Maryam Albaji, Samira Kafan, Roya Saedpanah, Amir Shokri, Elham Nazar   +7 more
wiley   +1 more source

When Chronic Pain Clouds Acute Diagnosis: Femoral Shaft Osteonecrosis With Superimposed Pseudomonas Osteomyelitis in a Medically Complex Patient

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT In medically complex patients with chronic pain, new or worsening symptoms should prompt careful reassessment. Avascular necrosis, particularly in the setting of prolonged steroid use, may be overlooked due to diagnostic overshadowing. Timely recognition requires multidisciplinary collaboration and vigilance to distinguish acute pathology from
Ji‐Hoon Lee, Elias Lai, Jerry Markar, Bi Mo   +3 more
wiley   +1 more source

Survival Improvement With Steroid Use for Pulmonary Veno‐Occlusive Disease With the Aid of Pulmonary Vasodilators and Tyrosine‐Kinase Inhibitor, a Retrospective Study

Clinical Cardiology, Volume 49, Issue 6, June 2026.
This study aimed to assess the efficacy of steroid treatment with pulmonary vasodilators and tyrosine kinase inhibitors in patients with Pulmonary VenoOcclusive Disease (PVOD). Kaplan‐Meier curve showed that survival of PVOD patients with PSL (PRS) was significantly better with Log rank test (p = 0.01) than without PSL (PNS).
Mayumi Finger, Kaori Takeuchi, Hanako Kikuchi, Ayumi Goda, Takumi Inami, Yuichi Tamura, Masaharu Kataoka, Toru Satoh   +7 more
wiley   +1 more source