Results 151 to 160 of about 2,315,835 (246)

Liver Fibrosis and IRS1 rs2972146 Are Associated With Weight Loss Response After Metabolic Bariatric Surgery

Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11532-11544, December 2026.
ABSTRACT Background and Aims Weight loss after metabolic bariatric surgery (MBS) is heterogeneous, and the contribution of liver histology and genetic susceptibility to insufficient weight loss (IWL) or weight regain (WR) remains unclear. We assessed the prevalence of IWL and WR after MBS and their association with liver histology and metabolic ...
Felice Cinque, Marica Meroni, Sara Badiali, Miriam Longo, Erika Paolini, Elisa Galfrascoli, Giovanna Oberti, Giuseppina Pisano, Gabriele Maffi, Matteo Mureddu, Elena Corbetta, Valentina Scimè, Emma Calzavara, Francesca Alletto, Annalisa Cespiati, Luigi Boni, Anna Ludovica Fracanzani, Paola Dongiovanni, Rosa Lombardi   +18 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, Volume 38, Issue 61, 2 November 2026.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Nasopharyngeal Carcinoma Mimicking Juvenile Nasopharyngeal Angiofibroma in an Adolescent Ghanaian Male: A Diagnostic Pitfall

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Nasopharyngeal carcinoma can mimic juvenile nasopharyngeal angiofibroma in adolescent males on both demographics and imaging; bilateral cavernous sinus involvement and sensorineural hearing loss are atypical for juvenile nasopharyngeal angiofibroma (JNA) and should prompt expedited tissue diagnosis even in settings where biopsy of a presumed ...
Dennis Brempong, Margaret Neizer, Samuel Romeo Hammond, Benedict Takyi   +3 more
wiley   +1 more source

Multivariable prediction model for suspected giant cell arteritis: development and validation

Clinical Ophthalmology, 2017
Edsel B Ing,1 Gabriela Lahaie Luna,2 Andrew Toren,3 Royce Ing,4 John J Chen,5 Nitika Arora,6 Nurhan Torun,7 Otana A Jakpor,8 J Alexander Fraser,9 Felix J Tyndel,10 Arun NE Sundaram,10 Xinyang Liu,11 Cindy TY Lam,1 Vivek Patel,12 Ezekiel Weis,13 David ...
Ing EB, Lahaie Luna G, Toren A, Ing R, Chen JJ, Arora N, Torun N, Jakpor OA, Fraser JA, Tyndel FJ, Sundaram ANE, Liu X, Lam CTY, Patel V, Weis E, Jordan D, Gilberg S, Pagnoux C, ten Hove M   +18 more
doaj  

Right Ventricular Dysfunction and Ventriculo‐Arterial Uncoupling in Heart Failure With Preserved Ejection Fraction: A Phenotype‐Specific Review of Mechanisms, Diagnosis, and Therapeutic Strategies

Clinical Cardiology, Volume 49, Issue 11, November 2026.
Right ventricular dysfunction affects 19%–33% of patients With heart failure With preserved ejection fraction and is associated With exercise intolerance, hospitalization, and mortality. Assessing right ventricular function and its coupling with the pulmonary circulation may improve risk stratification and support management tailored to distinct ...
Amarelle Chamoun, Talha Farooq, Suhayya Batool, Sadia Tameez‐ud—din, Muhammad Yousaf, Preet Memon, Mohsin Ali, Arun Kumar Maloth, F. N. U. Sawaira, Muhammad Taimur Khan, Mohammad Eisa Ali, Mansoor Khalid, Maleeha Pandit, Kamil Ahmad Kamil   +13 more
wiley   +1 more source

MEK1/2 Signalling establishes an alloreactive effector T cell program through SMAD4 during cardiac allograft rejection

Clinical and Translational Medicine, Volume 16, Issue 11, November 2026.
Upon T cell receptor (TCR) engagement by alloantigens, MEK1/2–ERK1/2 signalling promotes SMAD4 nuclear translocation and supports SMAD4‐dependent transcription of effector genes, including Ifng, Tnf, and Il2ra. This transcriptional program promotes alloreactive T cell effector function and contributes to cardiac allograft rejection.
Jiulu Zhao, Shuan Ran, Sijie Zhou, Yuan Li, Wang Zhan, Longyong Lai, Jikai Cui, Jiahong Xia, Jie Wu   +8 more
wiley   +1 more source

Beyond Pigmentation: Interplay of Metabolic Profile, Carotid Intima—Media Thickness, and Fatty Liver in Vitiligo: An Age‐ and Sex‐Matched Case‐Control Study

Health Science Reports, Volume 9, Issue 11, November 2026.
ABSTRACT Background and Aims Vitiligo shares inflammatory and metabolic pathways with cardiovascular and hepatic steatosis. Carotid intima–media thickness (IMT) is an established marker of early subclinical atherosclerosis, whereas non‐alcoholic fatty liver disease (NAFLD) reflects hepatic involvement in chronic inflammatory and metabolic dysregulation.
Mehrdad Mozafar, Yasamin Bigdeli, Mehdi Azizmohammad Looha, Reza Samiee, Safoura Shakoei, Ifa Etesami, Zeinab Aryanian, Faezeh Khorasanizadeh, Parvaneh Hatami   +8 more
wiley   +1 more source

Old disease, new twist

Journal of Hospital Medicine, Volume 21, Issue 11, Page 1305-1309, November 2026.
Abstract An 81‐year‐old man with a history of high‐grade urothelial carcinoma of the bladder and ureter on treatment with atezolizumab and tiragolumab presented to the emergency department with 5 months of malaise, generalized weakness, and fatigue and 2 weeks of subjective fevers. One month prior to presentation, he received an empiric 9‐day course of
Hadi Roudsari, Gurpreet Dhaliwal, Anand D. Jagannath, Alan H. Baik, Sam Brondfield   +4 more
wiley   +1 more source

Atherosclerosis: From Pathogenesis to Therapeutic Interventions

MedComm, Volume 7, Issue 11, November 2026.
The diagram outlines the core mechanisms driving atherosclerosis, including endothelial dysfunction, inflammatory responses, phenotypic switching of smooth muscle cells, and the gut–vascular axis. It also presents the corresponding therapeutic approaches now under development, such as gene therapies, immunotherapies, and nanotechnology platforms ...
Enge Zhou, Chenxi Zhan, Yuting Li, Yi Zeng, Renfei Luo, Xin Ouyang, Shixing Liu, Renqiang Yang, Nianlong Yan, Long Jiang   +9 more
wiley   +1 more source

Analysis of an acute care surgery service performing temporal artery biopsy for suspected giant cell arteritis. [PDF]

Surg Open Sci
Friend TH, Goosman M, Hancock A, Aluisio A, Oliveira N, Silva M, Dias E, Heffernan DS, Stephen AH.   +8 more
europepmc   +1 more source