Results 91 to 100 of about 2,094,770 (266)
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
EPJ Data Science, 2017 The immense growth of the social Web, which has made a large amount of user data easily and publicly available, has opened a whole new spectrum for research in social behavioral sciences. However, as the volume of social media content increases at a very
Vanessa Peña-Araya +3 more
doaj +1 more source
How do Households Value the Future? Evidence from Property Taxes [PDF]
, 2018 Despite the near ubiquity of inter-temporal choice, there is little consensus on the rate at which individuals trade present and future costs and benefits.
Koster, H. R. A., Pinchbeck, E.
core +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Temporal evolution of mesoscopic structure of some non-Euclidean systems using a Monte Carlo model
, 2011 A Monte Carlo based computer model is presented to comprehend the contrasting observations of Mazumder et al. [Phys. Rev. Lett. 93, 255704 (2004) and Phys. Rev.
D. Sen +4 more
core +1 more source
Attention Dynamics in Spatial-Temporal Contexts
Behavioral SciencesThis study systematically explored the impact of the spatial metaphor of time on attentional bias using visual order stimuli, ranging from fully order to 50% disorder, highlighting the regulatory roles of short-term memory and Gestalt perceptual grouping. Three experiments were conducted.
Wang, Yuying +2 more
openaire +3 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Heidegger’s Distinction between Scientific and Philosophical Judgments [PDF]
, 2007 Some commentators, such as Jürgen Habermas, think Martin Heidegger is guilty of a performative contradiction, because he uses judgments to situate judgments in a non-judicative context.
Engelland, Chad
core +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source