Results 231 to 240 of about 2,457,136 (299)

ICOS‐ImmunoPET Monitors T Cell Activation After Combination Immune Checkpoint Blockade in a Mouse Model of Melanoma Brain Metastasis

Advanced Science, EarlyView.
ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo, Rohit Verma, Sydney C. Nagy, Mausam Kalita, Samuel Aubert, Josué Ballesteros‐Álvarez, Pedro Machado Almeida, Hannes Vogel, Israt S. Alam, Michael Lim, Michelle L. James   +10 more
wiley   +1 more source

Host-virus association databases as tools for understanding viral spillover at varying scales. [PDF]

PLoS Negl Trop Dis
Lindsley IC, Juman MM, Seifert SN, Gibb R, Albery GF, Jephcott F, Restif O.   +6 more
europepmc   +1 more source

Deltacoronavirus Modulates circRNA cGLIS3 Metabolism to Evade Host Antiviral Response

Advanced Science, EarlyView.
This study reveals that both deltacoronavirus nucleocapsid protein and host RNA binding protein IGF2BP2 promote circular RNA GLIS3 (cGLIS3) biogenesis by binding to GLIS3 pre‐mRNA. The m6A modification‐mediated cGLIS3‐IGF2BP2 interaction weakens RNase L‐mediated degradation of cGLIS3 while facilitates a ubiquitin‐dependent degradation of IGF2BP2, thus ...
Liuyang Du, Liping Wang, Sujing Diao, Juan Li, Lei Zhao, Yan Yan, Haimin Li, Weiren Dong, Wei Wu, Jinyan Gu, Jiyong Zhou   +10 more
wiley   +1 more source

Mapping the Inflammation Research Landscape in Myocardial Infarction, 1995-2025: A Bibliometric Analysis of WoSCC and PubMed. [PDF]

J Inflamm Res
Liu Y, Chen S, Li T, Hu Y, Lin Z, Fu Y, Fu Z.   +6 more
europepmc   +1 more source

Miro1 Protects Against Acute Kidney Injury Through Modulating Mitochondrial Homeostasis via Interaction With Sirt6

Advanced Science, EarlyView.
Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu, Qing Li, Yiyang Xu, Zitao Wang, Hua Shu, Yangfan Wu, Fang Lu, Zhimin Huang, Bo Zhang, Hongwei Liang, Changying Xing, Huijuan Mao, Yanggang Yuan   +12 more
wiley   +1 more source

Machine Learning and Deep Learning for Earthquake Monitoring: A Systematic Review of Distributed Acoustic Sensing Applications. [PDF]

Sensors (Basel)
Iqbal N, Aziz IBA, Hakimi HSB, Raza MF, Rashid A.   +4 more
europepmc   +1 more source

Explainable artificial intelligence in medical ultrasound: a WoSCC-based bibliometric analysis, evidence map, and Scopus concordance assessment. [PDF]

Front Med (Lausanne)
Shi Z, Hu Z, Wang C, Yu C, Zhang W, Luo Y, Zhang C.   +6 more
europepmc   +1 more source

M3: Conversational LLMs simplify secure clinical data access, understanding, and analysis. [PDF]

PLOS Digit Health
Al Attrach R, Moreira P, Fani R, Umeton R, Fiske A, Celi LA.   +5 more
europepmc   +1 more source

Temporal trends in LDL cholesterol levels from 2009 to 2023: a comprehensive analysis of 2.4 million patient records in São Paulo, Brazil. [PDF]

Einstein (Sao Paulo)
Dias PRTP, Mariante QS, Lopes FPPL.
europepmc   +1 more source