Results 41 to 50 of about 2,457,136 (299)

Streamlining Temporal Formal Verification over Columnar Databases

Information
Recent findings demonstrate how database technology enhances the computation of formal verification tasks expressible in linear time logic for finite traces (LTLf).
Giacomo Bergami
doaj   +1 more source

Research on Temporal Query Expansion and Temporal Index Optimization Based on Spark [PDF]

Jisuanji gongcheng, 2017
There exists some temporal databases and temporal analysis tools based on cluster-based computing systems.However,most of them are disk-oriented and performance degenerate rapidly when processing big data.This paper proposes a system which is based on ...
ZHOU Liang,LI Gefei,TAI Weipeng,ZHENG Xiao
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Converting relational databases into object relational databases [PDF]

, 2010
This paper proposes an approach for migrating existing Relational DataBases (RDBs) into Object-Relational DataBases (ORDBs). The approach is superior to existing proposals as it can generate not only the target schema but also the data instances.
Ali, Akhtar, M. Akhtar Ali, Rossiter, Nick, Nick Rossiter, Abdelsalam Maatuk, Maatuk, Abdelsalam   +5 more
core   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Spatio-temporal multi-granularity : modelling and implementation challenges [PDF]

, 2009
Multiple spatial and temporal granularities are essential to extract significant knowledge from datasets at different levels of detail: they enable to zoom-in and zoom-out a dataset, enhancing the data modelling flexibility and being instrumental to ...
Elena Camossi, Camossi, Elena, Bertino, Elisa, Michela Bertolotto, Elisa Bertino, Bertolotto, Michela   +5 more
core   +1 more source

Metric-temporal access methods

Journal of Computer Science and Technology, 2010
Metric-temporal databases are a new database model that combines metric spaces with temporal databases to process similarity queries within a time interval or snapshot.
Anabella De Battista, Norma Edith Herrera, Gilberto A. Gutiérrez Retamal, Andrés Pascal   +3 more
doaj  

Durative Events in Active Databases [PDF]

, 2004
Active databases are DBMS which are able to detect certain events in the environment and trigger actions in consequence. Event detection has been subject of much research, and a number of different event specification languages is extant.
Augusto, Juan Carlos, Juan Carlos Augusto, Gomez, Rodolfo, Rodolfo Gomez   +3 more
core   +1 more source

Evolving temporal fuzzy itemsets from quantitative data with a multi-objective evolutionary algorithm [PDF]

, 2011
We present a novel method for mining itemsets that are both quantitative and temporal, for association rule mining, using multi-objective evolutionary search and optimisation.
Gongora, Mario A., Matthews, Stephen G., Gongora, M. A., Gongora, Mario Augusto, Stephen G. Matthews, Hopgood, Adrian, Matthews, S. G., Hopgood, Adrian A., Adrian A. Hopgood, Mario A. Gongora   +9 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source