Results 51 to 60 of about 2,457,136 (299)
BMC Medical Informatics and Decision Making, 2022 Background Temporal pattern discovery (TPD) is a method of signal detection using electronic healthcare databases, serving as an alternative to spontaneous reporting of adverse drug events.
M. Lavallee +6 more
doaj +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
A Scalable Approach to Historical Data Management via Optimized Transaction Logs
IEEE AccessTemporal databases play a crucial role in tracking the evolution of data over time by preserving historical states through valid time intervals instead of overwriting data.
Michal Kvet, Jarmila Skrinarova
doaj +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Concept and assumptions about the temporal graph database
MATEC Web of Conferences, 2018 The article outlines existing solutions in the area of graphs and temporal databases. It provides explanation for why the temporal graph database was created.
Koszela Jarosław +1 more
doaj +1 more source
Towards Temporal Graph Databases
CoRR, 2016 In spite of the extensive literature on graph databases (GDBs), temporal GDBs have not received too much attention so far. Temporal GBDs can capture, for example, the evolution of social networks across time, a relevant topic in data analysis nowadays. In this paper we propose a data model and query language (denoted TEG-QL) for temporal GDBs, based on
Alexander Campos +2 more
openaire +3 more sources
The representation and management of evolving features in geospatial databases [PDF]
, 2009 Geographic features change over time, this change being the result of some kind of event or occurrence. It has been a research challenge to represent this data in a manner that reflects human perception.
Lohfink, Alex
core
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
A Logic Programming Framework for Modelling Temporal Objects [PDF]
, 1996 Published ...
Kesim, N. +5 more
core +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source