Results 161 to 170 of about 96,886 (299)

Intracranial electroencephalographic connectivity analysis to localize epileptogenic networks: Systematic review and meta‐analysis from ILAE Epilepsy Surgery Networks Task Force

Epilepsia, EarlyView.
Abstract Intracranial electroencephalographic (iEEG) connectivity analysis is a promising method to localize epileptic networks and guide surgical planning in focal drug‐resistant epilepsy. Despite numerous studies exploring its utility, the added value of iEEG connectivity over standard clinical presurgical evaluation remains unclear.
Nishant Sinha, Daniel J. Zhou, Victoria L. Morgan, Dario J. Englot, Leonardo Bonilha, Milan Brázdil, Xiaosong He, Riki Masumoto, Quy Cao, Terence J. O'Brien, Chengyuan Wu, Erik Kaestner, Carrie McDonald, Ezequiel Gleichgerrcht, Aileen McGonigal, Kathryn A. Davis   +15 more
wiley   +1 more source

Long‐lasting remodeling of astrocytes in an Scna1+/− mouse model of Dravet syndrome

Epilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is a prototypical developmental and epileptic encephalopathy caused by mutations in the SCN1A gene, leading to loss of function of the voltage‐gated sodium channel Naᵥ1.1. The latter causes early onset drug‐resistant seizures and enduring cognitive and behavioral deficits.
Athénaïs Genin, Alicia Janvier, Tristan Moujellil‐Legagneur, Marine Blaquière, Alexis Chaussy, Romane Privé, Fabrice Duprat, Massimo Mantegazza, Etienne Audinat, Nicola Marchi, Noémie Cresto   +10 more
wiley   +1 more source

Open diffusion magnetic resonance imaging and connectivity data for epilepsy and surgery: The IDEAS II release

Epilepsia, EarlyView.
Abstract Objective Epileptic seizures are generated in cerebral networks that propagate ictal and interictal activity. The structure of cerebral networks underpinning epileptic activity can be inferred from diffusion‐weighted magnetic resonance imaging (DWI).
Peter N. Taylor, Gerard Hall, Jonathan Horsley, Yujiang Wang, Sjoerd B. Vos, Gavin P. Winston, Andrew W. McEvoy, Anna Miserocchi, Jane de Tisi, John S. Duncan   +9 more
wiley   +1 more source

Shining Light on the Neuropathology of Temporal Lobe Epilepsy. [PDF]

Epilepsy Curr
Scharfman HE.
europepmc   +1 more source

Contralateral language network integration predicts and protects against naming decline after temporal lobe resection

Epilepsia, EarlyView.
Abstract Objective Anterior temporal lobe resection (ATLR) is an effective treatment for drug‐resistant temporal lobe epilepsy (TLE) but carries a substantial risk of language impairment, particularly in naming. Understanding and predicting the impact of ATLR on language functions remains a major clinical challenge.
Karl‐Heinz Nenning, Karin Trimmel, Lisa Bartha‐Doering, Marc Berger, Matthias J. Koepp, Georg Langs, Gregor Kasprian, John S. Duncan, Silvia B. Bonelli   +8 more
wiley   +1 more source

Genetic and Neuroanatomical Support for Functional Brain Network Dynamics in Epilepsy

, 2018
Focal epilepsy is a devastating neurological disorder that affects an overwhelming number of patients worldwide, many of whom prove resistant to medication.
Bassett, Danielle S., Betzel, Richard F., Davis, Kathryn A., Khambhati, Ankit N., Kini, Lohith, Litt, Brian, Lucas, Thomas H., Reddy, Pranav G., Shah, Preya   +8 more
core  

Sleep magnetoencephalography enhances detection and source imaging of seizures and fast oscillations in focal cortical dysplasia

Epilepsia, EarlyView.
Abstract Objective Focal cortical dysplasia (FCD) causes drug‐resistant epilepsy requiring presurgical evaluation. Invasive electroencephalographic (EEG) studies demonstrate that sleep modulates epileptic activity, including interictal epileptiform discharges (IEDs), fast oscillations (FOs) in the beta (14–40 Hz) and gamma (40–80 Hz) frequency bands ...
Marcel Heers, Jawata Afnan, Christoph Braun, Christophe Grova, Dirk‐Matthias Altenmüller, Bernhard J. Steinhoff, Matthias Dümpelmann, Theo Demerath, Horst Urbach, Silke Ethofer, Markus Siegel, Andreas Schulze‐Bonhage, Holger Lerche, Yiwen Li Hegner   +13 more
wiley   +1 more source

The Role of GABA and Its Receptors in Temporal Lobe Epilepsy. [PDF]

Biomolecules
Sperk G, Pirker S.
europepmc   +1 more source

Interictal and seizure‐onset scalp electroencephalographic patterns in malformations of cortical development

Epilepsia, EarlyView.
Abstract Objective Malformations of cortical development (MCDs) are a frequent cause of drug‐resistant epilepsy and a common indication for resective epilepsy surgery. As magnetic resonance imaging (MRI) lacks sensitivity for subtle MCDs, supplemental diagnostic tools are needed.
Lubna Shakhatreh, Liz Edenberg P. Quiles, Zhibin Chen, Ofer M. Gonen, Saba Mohidat, Lyn Millist, Callum Hollis, Andrea Sundram, Piero Perucca, Terence J. O'Brien, Patrick Kwan   +10 more
wiley   +1 more source

Alterations in glymphatic system and brain morphology in patients with temporal lobe epilepsy. [PDF]

BMC Med Imaging
Huang X, Wang M, Wu Z, Jiang R, Lin W, Chen C, Xue Y, Wáng YXJ.   +7 more
europepmc   +1 more source