A dual-modality workflow for quantifying microvascular structure in human temporal lobe epilepsy. [PDF]
Xu Z +11 more
europepmc +1 more source
Raising resilience: A parenting intervention for families affected by childhood epilepsy
Abstract Objective Despite behavioral concerns reported among children with epilepsy, evidence‐based family‐focused interventions designed for this population remain limited. The objectives of this study were to characterize behavioral concerns and parent mental health needs in families of children with epilepsy relative to children with non‐epileptic ...
Samantha J. Feldman +4 more
wiley +1 more source
Stereo‐electroencephalography–guided responsive neuromodulation: A propensity‐matched cohort study
Abstract Objective The optimal pre‐implantation evaluation and surgical targeting strategies for responsive neurostimulation (RNS) in patients with unresectable, drug‐resistant focal epilepsy continue to be debated. Although stereo‐electroencephalography (sEEG) is central to characterizing the seizure‐onset zone, its role in preoperative testing for ...
David Botros +11 more
wiley +1 more source
Thalamocortical connectivity and nucleus-specific thalamic dysfunction in temporal lobe epilepsy: an integrative review. [PDF]
Bevacqua G +4 more
europepmc +1 more source
Abstract Objective Detection of epilepsy‐causing structural brain lesions on magnetic resonance imaging (MRI) is critical for diagnosis, prognosis, and treatment planning in people with epilepsy. We aimed to establish an epilepsy‐directed multisite harmonized 3‐T MRI acquisition protocol for the Australian Epilepsy Project (AEP) and describe the ...
David N. Vaughan +19 more
wiley +1 more source
Explainable Deep Learning for MRI-Negative Temporal Lobe Epilepsy: Classification and Brain Region Analysis. [PDF]
Wang H +7 more
europepmc +1 more source
WONOEP appraisal: Biomarkers and treatment strategies beyond the synapse
Abstract Epilepsy is a heterogeneous neurological disorder affecting more than 70 million people worldwide, posing significant challenges for clinicians due to its complex etiology, diverse manifestations, variable treatment responses, and the inability to predict seizures or disease onset reliably.
Mirte Scheper +11 more
wiley +1 more source
Rare genetic variation in adults with surgically treated temporal lobe epilepsy: An exome sequencing study. [PDF]
Pirker AP +12 more
europepmc +1 more source
Hippocampal network activity changes during early epileptogenesis predict subsequent epilepsy
Abstract Objective Despite decades of research, the circuit mechanisms that underlie focal epileptogenesis remain incompletely understood. In this study, we aimed to characterize the changes in hippocampal network activity induced by an epileptogenic insult.
Michael Strüber +13 more
wiley +1 more source
Lateralization of Bilateral Temporal Lobe Epilepsy After Vagus Nerve Stimulation Surgery. [PDF]
Wu HY, Chen PW, Chen C, Chen HH.
europepmc +1 more source

