Results 181 to 190 of about 96,886 (299)

Tissue oxygenation dynamics during transition from seizure to spreading depolarization in rat brain

open access: yesEpilepsia, EarlyView.
Abstract Objective Spreading depolarization (SD) is a phenomenon underlying various neurological conditions, including epilepsy. Researchers have suspected that local tissue oxygenation breakdown induces spontaneous SD. In this study, we investigated the relationship between spontaneous epileptic seizures and SD, with a focus on the role of local ...
Jiayang Liu, Bruce J. Gluckman
wiley   +1 more source

The usefulness of intraoperative electrocorticography (iECoG) in pediatric temporal lobe epilepsy surgery. [PDF]

open access: yesEpileptic Disord
Cruz RA   +8 more
europepmc   +1 more source

Ranking of antiseizure medications in a panel of focal seizure models predicts their comparative efficacy in clinical add‐on trials in drug‐resistant focal epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Most antiseizure medications (ASMs) have been discovered by testing in animal models, which are generally thought to predict antiseizure activity in patients. However, it is not known whether any of these models (or a combination of models) can predict whether a novel ASM exhibits higher clinical efficacy in focal drug‐resistant ...
Wolfgang Löscher, Pavel Klein
wiley   +1 more source

Hippocampal interictal discharges induce frontal spindles and enhance spindle-slow oscillation coupling in temporal lobe epilepsy. [PDF]

open access: yesClin Neurophysiol Pract
Uehara T   +10 more
europepmc   +1 more source

Deep brain stimulation of the thalamus for intractable epilepsy (FRANCE study): A randomized clinical trial

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate the efficacy and safety of deep brain stimulation (DBS) of the anterior nucleus of the thalamus (ANT) compared with best medical treatment (BMT) in patients with drug‐resistant epilepsy (DRE).
Stéphan Chabardès   +30 more
wiley   +1 more source

Performance of the 5‐SENSE score in a pediatric and young adult cohort of 100 consecutive stereoelectroencephalography cases

open access: yesEpilepsia, EarlyView.
Abstract This study assesses the validity of the 5‐SENSE score in a cohort of pediatric patients with epilepsy and evaluates associations between the score, ancillary testing, and surgical outcomes. We retrospectively calculated the 5‐SENSE score in a single‐center predominantly pediatric cohort and calculated the sensitivity and specificity for ...
Lindsey Trank   +7 more
wiley   +1 more source

Single voxel autocorrelation reflects hippocampal function in temporal lobe epilepsy. [PDF]

open access: yesImaging Neurosci (Camb)
Bouffard NR   +5 more
europepmc   +1 more source

Intracranial electroencephalographic approaches in the intensive care unit: Safety, feasibility, and coverage

open access: yesEpilepsia, EarlyView.
Abstract Objective Nonconvulsive epileptic activity is common after acute brain injury and contributes to neuronal injury and poor outcomes. Although intracranial electroencephalography (iEEG) improves detection compared with surface EEG (suEEG), it currently relies on focal recordings of epileptic dynamics.
Steven Smeijers   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy