Brain connectivity signatures of cognitive impairment in temporal lobe epilepsy identified by robotic assessment. [PDF]
Garcia-Ramo KB +10 more
europepmc +1 more source
Stereo‐EEG mapping of visual working memory with task‐related high‐gamma modulations
Abstract Objective We describe a safe, informative, and easy‐to‐implement approach for presurgical mapping of visual working memory (VWM) with stereo‐electroencephalography (SEEG). Methods Twenty‐four patients with drug‐resistant epilepsy, 11–23 years of age, performed a single‐probe change detection VWM task, during SEEG monitoring.
Brian Ervin +13 more
wiley +1 more source
Novel Genetic Insights into Lateral Temporal Lobe Epilepsy: Findings from Whole Exome Sequencing. [PDF]
Salman B +7 more
europepmc +1 more source
Abstract Objective Circulating small noncoding RNAs represent potential biomarkers of temporal lobe epilepsy (TLE). Recently, two transfer RNA fragments (tRFs), 5′tRF Glu‐CTC and Gly‐GCC, were found to be elevated in plasma samples collected in advance of a seizure in TLE patients, suggesting they may serve as potential wet biomarkers of seizure risk ...
Marie Soukupova +15 more
wiley +1 more source
Numbers of Granule Cells and GABAergic Boutons Are Correlated in Shrunken Sclerotic Hippocampi of Sea Lions with Temporal Lobe Epilepsy. [PDF]
Wyeth M +4 more
europepmc +1 more source
Abstract Objective Sigma‐1 is a chaperone protein that serves as a key homeostatic regulator, implicated in neuronal excitability and seizure control. Positive allosteric modulators offer a use‐dependent means to enhance Sigma‐1 activity, potentially with favorable tolerability compared to direct agonists.
Eva‐Lotta von Rüden +5 more
wiley +1 more source
A Kaleidoscope of Cognitive Vulnerability in Temporal Lobe Epilepsy. [PDF]
Zawar I.
europepmc +1 more source
Creativity and its link to epilepsy
Abstract Creative thinking represents one of our highest‐order cognitive processes, involving multiple cortical structures and an intricate interplay between several cortical and subcortical networks. It results in novel ideas that translate to useful products or concepts. The evolutionary purpose of creativity is therefore apparent, as it advances our
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Divergent Propagation Networks Define Two Pathophysiologically Distinct Electroclinical Phenotypes in Mesial Temporal Lobe Epilepsy. [PDF]
Bae H +4 more
europepmc +1 more source
Gut‐microbiota‐brain Axis and post‐traumatic epilepsy
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley +1 more source

