Results 221 to 230 of about 57,363 (307)

WONOEP appraisal: Biomarkers and treatment strategies beyond the synapse

Epilepsia, EarlyView.
Abstract Epilepsy is a heterogeneous neurological disorder affecting more than 70 million people worldwide, posing significant challenges for clinicians due to its complex etiology, diverse manifestations, variable treatment responses, and the inability to predict seizures or disease onset reliably.
Mirte Scheper, Zining Liu, Aristea S. Galanopoulou, Gernot Hlauschek, Benjamin Sinclair, Wai Lam Leung, Stefanie Dedeurwaerdere, Elisabeth Doran, Solomon L. Moshé, David C. Henshall, Ozlem Akman, Pablo M. Casillas‐Espinosa   +11 more
wiley   +1 more source

Novel Genetic Insights into Lateral Temporal Lobe Epilepsy: Findings from Whole Exome Sequencing. [PDF]

Noro Psikiyatr Ars
Salman B, Kesim Y, Şirin NG, Süsgün S, Uzun GA, İşeri SU, Bebek N, Baykan B.   +7 more
europepmc   +1 more source

Hippocampal network activity changes during early epileptogenesis predict subsequent epilepsy

Epilepsia, EarlyView.
Abstract Objective Despite decades of research, the circuit mechanisms that underlie focal epileptogenesis remain incompletely understood. In this study, we aimed to characterize the changes in hippocampal network activity induced by an epileptogenic insult.
Michael Strüber, Tristan Manfred Stöber, Vanessa Schütz, Lara Costard, Valentin Neubert, Sebastian Bauer, Parsa Gharavi, Julika Pitsch, Nico Melzer, Adam Strzelczyk, Jochen Triesch, Kai Siebenbrodt, Felix Rosenow, Ricardo Kienitz   +13 more
wiley   +1 more source

Numbers of Granule Cells and GABAergic Boutons Are Correlated in Shrunken Sclerotic Hippocampi of Sea Lions with Temporal Lobe Epilepsy. [PDF]

eNeuro
Wyeth M, Krucik DDR, Thorbrogger CJ, Field C, Buckmaster PS.   +4 more
europepmc   +1 more source

Hypergraphia in temporal lobe epilepsy

Annals of Indian Academy of Neurology, 2009
openaire   +2 more sources

Ventral anterior thalamic dysfunction distinguishes seizure generalization in temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective Focal‐to‐bilateral tonic–clonic seizures (FBTCS) in temporal lobe epilepsy (TLE) involve thalamocortical networks, yet the functional integrity and role of specific thalamic subregions in seizure generalization remain unclear. In this cross‐sectional study, we investigated whether thalamic subregion functional connectivity patterns ...
Stacy N. Hudgins, Michael R. Sperling, Hasan Ayaz, Joseph I. Tracy   +3 more
wiley   +1 more source

Zingerone alleviates acute seizures by reducing intrinsic hippocampal neuronal excitability in a rat model of temporal lobe epilepsy. [PDF]

Front Neurosci
Ni H, Yang W, Han S, Wang Y, Ding H, Song T, Zhang M, Yu J, Ge R.   +8 more
europepmc   +1 more source

Postoperative reduction of anti‐seizure medication is associated with cognitive improvement in seizure‐free patients after anterior temporal lobectomy

Epilepsia, EarlyView.
Abstract Objective To determine whether postoperative reduction of anti‐seizure medication (ASM) burden is associated with cognitive improvement after anterior temporal lobectomy (ATL) in seizure‐free patients. Methods We retrospectively analyzed data for adult patients with drug‐resistant temporal lobe epilepsy who underwent unilateral ATL between ...
Kazushi Ukishiro, Shin‐ichiro Osawa, Maimi Ogawa, Makoto Ishida, Takafumi Kubota, Kazutoshi Konomatsu, Hidenori Endo, Kazutaka Jin   +7 more
wiley   +1 more source

Neuroprotective Effects of Anodal tDCS on Oxidative Stress and Neuroinflammation in Temporal Lobe Epilepsy. [PDF]

Biomedicines
Arslan AO, Akcay S, Akcay G, Zaqzouq D, Him A.   +4 more
europepmc   +1 more source

Characterizing chapeau de gendarme in pediatric epilepsy through systematic video‐EEG evaluation

Epilepsia, EarlyView.
Abstract Objective Chapeau de gendarme (CdG) is a subtle but clinically relevant semiology that has been scarcely studied in children. Previous studies have primarily focused on its localizing value in small, surgical cohorts. This study aimed to systematically characterize frequency and clinical features of CdG across the pediatric age spectrum ...
Hanna Barbara Brinkmann, Lea Nakamura, Jan Schönberger, Julia Jacobs, Victoria San Antonio‐Arce, Kerstin Alexandra Klotz   +5 more
wiley   +1 more source