Results 231 to 240 of about 96,886 (299)

Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges

Epilepsia Open, EarlyView.
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus, Cesar Santana‐Gomez, Ruby G. Escalante, Dominique Duncan, Pedro F. Viana, Giulia Sofia Cereda, Naoto Kuroda, Aristea S. Galanopoulou   +7 more
wiley   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

Detection of interictal epileptiform discharges using multiple bilateral insertions of a newly developed microcatheter‐compatible endovascular electroencephalogram electrode: A clinical feasibility trial

Epilepsia Open, EarlyView.
Abstract Objective To assess the feasibility, technical performance, and safety of a novel endovascular electroencephalogram (eEEG) electrode, EP‐01, designed for minimally invasive seizure localization in patients with drug‐resistant epilepsy. Methods This single‐center, prospective, exploratory trial enrolled five patients with drug‐resistant ...
Kota Araki, Yosuke Masuda, Ayataka Fujimoto, Mitsuyo Nishimura, Hisayuki Hosoo, Hiroki Ishida, Takashi Enokizono, Kensuke Kawai, Eiichi Ishikawa, Yuji Matsumaru   +9 more
wiley   +1 more source

Epilepsy surgery: From bench to the clinics

Epilepsia Open, EarlyView.
Abstract Objective Recent advances in epilepsy surgery in patients with intractable epilepsy make it possible to study the mechanism of epilepsy in human brains. However, the true extent and propagation of each epileptogenic area from the epileptogenic focus in each patient is still difficult to perform “epilepsy cure” by surgery.
Tatsuya Tanaka
wiley   +1 more source

High frequency deep brain stimulation of the hippocampus in a rat model for temporal lobe epilepsy [PDF]

, 2006
Boon, Paul, CLAEYS, P, De Smedt, Tim, Leybaert, Luc, Mabilde, Cyriel, Raedt, Robrecht, Van den broecke, Caroline, Wadman, Wytse, Waterschoot, Liesbeth, Wyckhuys, Tine   +9 more
core   +1 more source

Scalp fast oscillations detected by high-density EEG as a noninvasive predictor of surgical outcome in temporal lobe epilepsy with hippocampal sclerosis. [PDF]

Epilepsia Open
Kongsakorn P, Jirasakuldej S, Treesuthacheep P, Surawattanawong T, Limotai C.   +4 more
europepmc   +1 more source

ENCEVIS: Evaluating the feasibility of an AI‐based algorithm as an assistant to neurophysiologists in clinical practice

Epilepsia Open, EarlyView.
Abstract Objective This study evaluated the performance of the ENCEVIS artificial intelligence (AI)‐based algorithm as a screening tool to predict the presence of ictal and/or interictal epileptiform discharges (IEDs) in electroencephalography (EEG) recordings.
Aleksandre Tsereteli, Natela Okujava, Nikoloz Malashkhia, Tamar Sakvarelidze   +3 more
wiley   +1 more source

Multimodal integration of magnetic resonance imaging and intracranial electroencephalographic abnormalities in temporal lobe epilepsy surgery. [PDF]

Epilepsia
Kozma C, Horsley J, Hall G, Simpson C, de Tisi J, Miserocchi A, Diehl B, McEvoy AW, Vos SB, Winston GP, Wang Y, Duncan JS, Taylor PN.   +12 more
europepmc   +1 more source

Evaluating the task‐specificity model of verbal memory: Regional volumetric analyses in temporal lobe epilepsy with hippocampal sclerosis

Epilepsia Open, EarlyView.
Abstract Objective Verbal memory tasks differ in their cognitive demands and may rely on distinct left medial temporal structures. One model holds that verbal delayed recall is hippocampal dependent, whereas verbal paired associate learning relies on adjacent rhinal cortex.
Andy Sitoh, David Weintrob, Jacqueline F. I. Anderson, Heath R. Pardoe, Marie F. O'Shea, Graeme D. Jackson, Piero Perucca, Chris Tailby   +7 more
wiley   +1 more source