Results 231 to 240 of about 1,806,075 (294)

Alterations in glymphatic system and brain morphology in patients with temporal lobe epilepsy. [PDF]

open access: yesBMC Med Imaging
Huang X   +7 more
europepmc   +1 more source

Abnormal KCC2 expression and function in a mouse model of epilepsy and tuberous sclerosis complex

open access: yesEpilepsia, EarlyView.
Abstract Objective Drug‐resistant epilepsy is a common, severe manifestation of the genetic disorder tuberous sclerosis complex (TSC). Although significant mechanistic and therapeutic advances have been made in TSC, treatments for seizures remain largely ineffective.
Dongjun Guo   +4 more
wiley   +1 more source

Epileptic arousals: A neglected clinical entity

open access: yesEpilepsia, EarlyView.
Abstract Objective Epileptic arousals (EAs) are seizures characterized solely by arousal from sleep. EAs are unrecognized in current seizure classifications. Their subtle semiology and inconsistently detectable ictal activity in scalp electroencephalography (EEG) complicate differentiation from physiological arousals (PAs). This study characterizes EAs
Lea Fisel   +8 more
wiley   +1 more source

Moving beyond spike detection: High frequency‐driven masking improves seizure onset zone localization in intracranial electroencephalography

open access: yesEpilepsia, EarlyView.
Abstract Objective Interictal epileptiform spikes (IESs) are widely used biomarkers of epileptogenic tissue in presurgical epilepsy evaluation. However, their reliability for seizure onset zone (SOZ) localization in high‐density intracranial electroencephalography (iEEG) remains inconsistent.
Amir Hossein Ayyoubi   +16 more
wiley   +1 more source

Automated segmentation of postsurgical resection cavities on magnetic resonance imaging in focal epilepsy: A Multicentre Epilepsy Lesion Detection study

open access: yesEpilepsia, EarlyView.
Abstract Objective Quantitative assessment of extent of tissue resection following epilepsy surgery requires accurate delineation of the resection cavity on postoperative magnetic resonance imaging (MRI). Current methods for resection cavity masking are time‐consuming and labor‐intensive, and existing automated approaches exhibit variable segmentation ...
Jieun Seo   +91 more
wiley   +1 more source

Abnormal functional connectivity patterns in temporal lobe epilepsy-An international ENIGMA-epilepsy study. [PDF]

open access: yesEpilepsia Open
Ives-Deliperi V   +29 more
europepmc   +1 more source

Nucleus basalis functional connectivity aberrations in temporal lobe epilepsy and improvements after successful epilepsy surgery

open access: yesEpilepsia, EarlyView.
Abstract Objective Resective surgery achieves seizure freedom in approximately 60%–80% of patients with drug‐resistant temporal lobe epilepsy (TLE), yet the extent to which seizure cessation permits recovery of disrupted functional brain networks remains unclear.
Addison C. Cavender   +15 more
wiley   +1 more source

Cross-species transcriptomic analysis of rodent model fidelity to human mesial temporal lobe epilepsy. [PDF]

open access: yesNat Commun
Kim J   +8 more
europepmc   +1 more source

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