Ventral anterior thalamic dysfunction distinguishes seizure generalization in temporal lobe epilepsy
Abstract Objective Focal‐to‐bilateral tonic–clonic seizures (FBTCS) in temporal lobe epilepsy (TLE) involve thalamocortical networks, yet the functional integrity and role of specific thalamic subregions in seizure generalization remain unclear. In this cross‐sectional study, we investigated whether thalamic subregion functional connectivity patterns ...
Stacy N. Hudgins +3 more
wiley +1 more source
Unsupervised clustering of electroclinical features in temporal lobe epilepsy: A data-driven approach. [PDF]
Vlachou M +8 more
europepmc +1 more source
Abstract Objective To determine whether postoperative reduction of anti‐seizure medication (ASM) burden is associated with cognitive improvement after anterior temporal lobectomy (ATL) in seizure‐free patients. Methods We retrospectively analyzed data for adult patients with drug‐resistant temporal lobe epilepsy who underwent unilateral ATL between ...
Kazushi Ukishiro +7 more
wiley +1 more source
Cognitive and Biomarker Signatures of Late-Onset Temporal Lobe Epilepsy: Toward Non-Alzheimer Neurodegenerative Mechanisms. [PDF]
Casarini A +18 more
europepmc +1 more source
Characterizing chapeau de gendarme in pediatric epilepsy through systematic video‐EEG evaluation
Abstract Objective Chapeau de gendarme (CdG) is a subtle but clinically relevant semiology that has been scarcely studied in children. Previous studies have primarily focused on its localizing value in small, surgical cohorts. This study aimed to systematically characterize frequency and clinical features of CdG across the pediatric age spectrum ...
Hanna Barbara Brinkmann +5 more
wiley +1 more source
Convergent functional networks of intrinsic activity alterations in temporal lobe epilepsy and their molecular correlates. [PDF]
Ma LL +7 more
europepmc +1 more source
Oligogenic inheritance in epilepsy: A systematic exome‐wide analysis
Abstract Objective Genetic factors contribute to the majority of epilepsies, but the exact genetic cause remains unknown in most patients. Incomplete penetrance and variable expressivity are frequent, and recent studies showed a burden of deleterious variants in epilepsy genes, suggesting a role for oligogenic inheritance.
Sarah Duerinckx +192 more
wiley +1 more source
Autism Spectrum Disorder, Temporal Lobe Epilepsy, and Treatment-Resistant Schizophrenia With Media-Themed Delusions and Impaired Insight: A Case Report. [PDF]
Turkson M +3 more
europepmc +1 more source
Does age influence diagnostic outcomes in an adult cohort referred to a first‐seizure clinic?
Abstract Objective The aging Danish population is associated with increasing morbidity and healthcare utilization. This study examines age‐related differences in resource utilization and diagnostic outcomes between older (65–95 years) and younger adults (18–64 years) evaluated for suspected epilepsy, including clinical management, diagnostic yield, and
Anne Line Lund Birkmose +3 more
wiley +1 more source
The spatial learning task of Lhermitte and Signoret: Marker of bilateral hippocampal dysfunction in temporal lobe epilepsy. [PDF]
Sitoh A +6 more
europepmc +1 more source

