Results 61 to 70 of about 341,873 (266)
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
ChildrenBackground: Life satisfaction serves as a preventive agent against various emotional, cognitive, and behavioral challenges, making it a crucial cognitive indicator of subjective well-being, particularly during adolescence.
Santiago Gómez-Paniagua +3 more
doaj +1 more source
Towards Multidecadal Consistent Meteosat Surface Albedo Time Series
Remote Sensing, 2010 Monitoring of land surface albedo dynamics is important for the understanding of observed climate trends. Recently developed multidecadal surface albedo data products, derived from a series of geostationary satellite data, provide the opportunity to ...
Alexander Loew, Yves Govaerts
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
On the Variability in the Temporal Stability Pattern of Soil Moisture Under Mediterranean Conditions
Spanish Journal of Soil ScienceIn recent decades, there has been increasing interest in studying the variability in soil water properties and, specifically, the spatiotemporal variability in the soil water content.
Ángel González-Zamora +2 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Journal of Hydrology and Hydromechanics, 2019 Subtropical regions have clay-rich, weathered soils, and long dry periods followed by intense rainfall that produces large fluctuations in soil water content (SWC) and hydrological behavior.
Gao Lei +4 more
doaj +1 more source