Results 91 to 100 of about 1,257,382 (329)

Lipophilic Toxins in Galicia (NW Spain) between 2014 and 2017: Incidence on the Main Molluscan Species and Analysis of the Monitoring Efficiency

open access: yesToxins, 2019
Galicia is an area with a strong mussel aquaculture industry in addition to other important bivalve mollusc fisheries. Between 2014 and 2017, 18,862 samples were analyzed for EU regulated marine lipophilic toxins. Okadaic acid (OA) was the most prevalent
Juan Blanco   +3 more
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Temporal variability of available phosphorus, potassium and magnesium in arable soil

open access: yesPlant, Soil and Environment, 2004
The investigation is focused on the illustration of the temporal changes in spatial variability of the Mehlich III available phosphorus, potassium and magnesium in the 10.5 hapart of the whole 54 hafield, located near Český Brod. Soil is characterized as
K. Štípek   +4 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Variabilidad temporal de la abundancia de Coralliophila abbreviata y Coralliophila caribaea (Mollusca, Coralliophilidae) en un arrecife coralino del Parque Nacional Morrocoy, Venezuela

open access: yesRevista de Biología Tropical, 2008
C. abbreviata y C. caribaea son moluscos coralívoros del Mar Caribe. Evaluamos la variabilidad temporal de la abundancia y los cambios en la estructura de talla de C. abbreviata y C. caribaea en Cayo Sombrero, Venezuela (septiembre 2004-agosto 2005).
Carlos del Mónaco   +2 more
doaj  

Evidence of an Internal Dissipation Origin for the High-energy Prompt Emission of GRB 170214A

open access: yes, 2017
The origin of the prompt high-energy ($>100$MeV) emission of Gamma-ray Bursts (GRBs), detected by the Large Area Telescope (LAT) on board the Fermi Gamma-ray Space Telescope, is still under debate, for which both the external shock origin and internal ...
Liu, Ruo-Yu   +2 more
core   +1 more source

Neural, electrophysiological and anatomical basis of brain-network variability and its characteristic changes in mental disorders [PDF]

open access: yes, 2016
Functional brain networks demonstrate significant temporal variability and dynamic reconfiguration even in the resting state. Currently, most studies investigate temporal variability of brain networks at the scale of single (micro) or whole-brain (macro)
Benjamin Becker   +10 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Methane emissions from underground gas storage in California

open access: yesEnvironmental Research Letters, 2020
Accurate and timely detection, quantification, and attribution of methane emissions from Underground Gas Storage (UGS) facilities is essential for improving confidence in greenhouse gas inventories, enabling emission mitigation by facility operators, and
Andrew K Thorpe   +16 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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