Results 91 to 100 of about 80,704 (296)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Museum temporality

open access: yesШаги
A review of: Walklate, J. (2023). Time and the museum: Literature, phenomenology, and the production of radical temporality. Routledge. 210 p.
V. K. Karnaukh
doaj  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

L’apport des neurosciences au modèle de l’Identité-Logement : Les stratégies d’apprentissage des personnes âgées concernées par la chute

open access: yesÉducation et Socialisation, 2018
Prevention of falls among the elderly, supported by home improvement strategies and changes in habits, raises the issue of learning. The concept of home-identity links the learning strategies of the elderly inhabitant with his or her temporality and ...
Frédérique TRÉVIDY   +2 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Temporal Clustering

open access: yesCoRR, 2017
27 pages, 10 ...
Dey, Tamal K.   +2 more
openaire   +6 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

A temporalidade como elemento chave no estudo das transformações no trabalho [PDF]

open access: yesAthenea Digital, 2003
The present article proposes an analysis concerning possible transformations of work based upon the concept of temporality. It considers the comprehension of the time category by the social sciences since the elaboration of the concept of social time to
Braz de Aquino, Cássio Adriano
doaj  

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

UNCONTROLLABILITY AND TEMPORALITY

open access: yesВестник Кемеровского государственного университета, 2013
The paper considers the influence of the semantics of uncontrollability on the use of verbs in different tense forms.
T. G. Pismak
doaj  

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