Results 71 to 80 of about 189,130 (309)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

City of Permanent Temporality

open access: yesJoelho, 2018
On July 22nd, 2001, there was the third shooting in a month. The municipality of Rotterdam declared the area around Rotterdam Centraal Station a zero-tolerance zone, installed 360o security cameras, and imposed the umpteenth ban on disreputable ...
Elma van Boxel   +2 more
doaj   +1 more source

A 2-dimensional Geometry for Biological Time [PDF]

open access: yes, 2011
This paper proposes an abstract mathematical frame for describing some features of biological time. The key point is that usual physical (linear) representation of time is insufficient, in our view, for the understanding key phenomena of life, such as ...
Bailly   +29 more
core   +4 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Timelessness, Trinity and temporality

open access: yesActa Academica, 2011
In philosophy and theology there exists a complex relation between timelessness, Trinity and temporality. Timelessness is an age-old attribute given to God in philosophical and theological traditions, but within the last century’s development of ...
Anné Verhoef
doaj   +3 more sources

Temporality and suicidal behaviour

open access: yesCultura de los Cuidados, 2012
Objetive: To evaluate the temporality and the psicosocial profile of some suicidal behaviours that were taken care of in the Asturias Central University Hospital (HUCA). Design: Prospective study.
Juan Luis López Rodríguez   +4 more
doaj   +1 more source

Temporal centering [PDF]

open access: yesProceedings of the 31st annual meeting on Association for Computational Linguistics -, 1993
We present a semantic and pragmatic account of the anaphoric properties of past and perfect that improves on previous work by integrating discourse structure, aspectual type, surface structure and commonsense knowledge. A novel aspect of our account is that we distinguish between two kinds of temporal intervals in the interpretation of temporal ...
Megumi Kameyama   +2 more
openaire   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Thinking About Events: A Pragmatist Account of the Objects of Episodic Hypothetical Thought [PDF]

open access: yes, 2018
The debate over the objects of episodic memory has for some time been stalled, with few alternatives to familiar forms of direct and indirect realism being advanced.
Michaelian, Kourken, Sant’Anna, André
core   +3 more sources

Home - About - Disclaimer - Privacy