Results 71 to 80 of about 80,704 (296)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The inner life of time. Nature across generations
Studi di Estetica, 2022 This contribution proposes to reflect on a different way of considering the link be-tween temporality and nature, between aiôn and physis, in dialogue with the words and works of the Italian sculptor Giuseppe Penone.
Pier Alberto Porceddu Cilione
doaj
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Temporality and suicidal behaviour
Cultura de los Cuidados, 2012 Objetive: To evaluate the temporality and the psicosocial profile of some suicidal behaviours that were taken care of in the Asturias Central University Hospital (HUCA). Design: Prospective study.
Juan Luis López Rodríguez +4 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
The role of temporality and interaction in the Turkey-EU relationship
, 2009 This paper introduces the two factors of temporality and interaction, which are not well-researched within the Turkey-EU relationship. I suggest that these two factors are important for understanding the process of Europeanization in Turkey and ...
Eralp, Atila
core
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Wonder: Temporality and educational value [PDF]
, 2020 This paper argues that wonder’s temporality and temperament helpexplain its educational value; and that to some extent its educationalvalue is closely connected with its temporality and its temperament.Much of ordinary life, including education (in the ...
Schinkel, Anders; id_orcid +1 more
core +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Social Psychology of Facts, Processes and Projects. Object and Time [PDF]
Athenea Digital, 2006 A dimension that must be considered, in the reflection that social sciences offer to society, is temporality. I would like to highlight the implicit idea of temporality within the different forms of psychosocial knowledge.
Gil, Adriana
doaj