Results 71 to 80 of about 29,219 (267)
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Éducation et Socialisation, 2018 Prevention of falls among the elderly, supported by home improvement strategies and changes in habits, raises the issue of learning. The concept of home-identity links the learning strategies of the elderly inhabitant with his or her temporality and ...
Frédérique TRÉVIDY +2 more
doaj +1 more source
Temporal Cycle Detection and Acyclic Temporization
CoRRIn directed graphs, a cycle can be seen as a structure that allows its vertices to loop back to themselves, or as a structure that allows pairs of vertices to reach each other through distinct paths. We extend these concepts to temporal graph theory, resulting in multiple interesting definitions of a "temporal cycle". For each of these, we consider the
Davi de Andrade +5 more
openaire +2 more sources
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
ШагиA review of: Walklate, J. (2023). Time and the museum: Literature, phenomenology, and the production of radical temporality. Routledge. 210 p.
V. K. Karnaukh
doaj
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
UNCONTROLLABILITY AND TEMPORALITY
Вестник Кемеровского государственного университета, 2013 The paper considers the influence of the semantics of uncontrollability on the use of verbs in different tense forms.
T. G. Pismak
doaj