Results 61 to 70 of about 29,219 (267)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Social Psychology of Facts, Processes and Projects. Object and Time [PDF]
Athenea Digital, 2006 A dimension that must be considered, in the reflection that social sciences offer to society, is temporality. I would like to highlight the implicit idea of temporality within the different forms of psychosocial knowledge.
Gil, Adriana
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Епістемологічні дослідження у філософії, соціальних і політичних наукахThe aim of this work is to investigate and conceptualize the ‘temporality regime’ as a socio-cultural phenomenon, primarily analyzing its impact on social processes and social transformations. This study characterizes the concept of ‘temporality regime’
Ярослав Юрійович ЖАРКО
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
A temporalidade como elemento chave no estudo das transformações no trabalho [PDF]
Athenea Digital, 2003 The present article proposes an analysis concerning possible transformations of work based upon the concept of temporality. It considers the comprehension of the time category by the social sciences since the elaboration of the concept of social time to
Braz de Aquino, Cássio Adriano
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Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Temporalité trans : identité de genre, temps transitoire et éthique médiatique
Enfances, Familles, Générations, 2017 Research Framework: The notions of “queer time” and “crip time” (queer and disabled temporalities) in queer and disability studies are descriptive and normative. On one hand, these notions represent a description of dominant temporality (heterosexual and
Alexandre Baril
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A Review of Sabzawari's Innovation in the Temporality of Universe: Nominal Temporality [PDF]
حکمت اسرا, 2014 The theory of nominal temporality, which is one of Sabzawari's innovations, has undergone three stages in his thought. To explain the doctrine, Sabzawari's words have some ambiguity, complexity and contradictions.
حسینعلی شیدان شید +1 more
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