Results 61 to 70 of about 80,704 (296)

Transitional Temporality

, 2020
Sewell (1996) identified three temporalities which underlie many social scientific accounts. This paper identifies a fourth: transitional temporality. This approach is inspired by Polanyi's (1944) comparative analysis of the rate of change of economic ...
Daniel Hirschman
core   +1 more source

Phenomenology of the Future:The temporality of objects beyond the temporality of inner-time consciousness [PDF]

, 2023
Based on a creative use of the phenomenological method, we argue that a close examination of the temporality of objects reveals the future as genuinely open. Without aiming to decide the matter of phenomenological realism, we suggest that this method can
Neumann, Daniel, Röck, Tina; id_orcid
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Time in the History of Art : Temporality, Chronology, and Anachrony

, 2018
Art history as we know it is regarded by many actors in the art world as obsolete. Today, it seems contemporaneity rules in a “post-historical” situation, where art history seems deprived of a future.
Karlholm, Dan,, Moxey, K.,, Moxey, Keith,   +2 more
core   +1 more source

Making Time for Critique: Canadian ‘Right to Shelter’ Debates in a Chrono-Political Frame

The Windsor Yearbook of Access to Justice, 2020
This article engages with Canadian ‘right to shelter’ discourse, with a focus on shared assumptions that do crucial work but are sometimes unstated.
Mark Zion
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Time and temporality as mediators of science learning [PDF]

, 2007
Few studies have focused on understanding how teaching and learning in classrooms are mediated by other dimensions of the organizational systems of which education is an integral part.
Kenneth Tobin, Tobin, Kenneth, Roth, W-M, Stephen M. Ritchie, Ritchie, S.M., Wolff-Michael Roth, Tobin, K., Ritchie, Stephen M., Roth, Wolff-Michael   +8 more
core   +2 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Temporality in Heidegger’s Early Thought [PDF]

Journal of Philosophical Investigations, 2019
For the establishment of the fundamental ontology, early Heidegger disregards the vulgar understanding of time and analyzes temporality. He believes that the vulgar understanding of time is the degeneration of the world-time, and the world-time itself is
Ehsan Nazari, Seyed Masoud Sayf
doaj   +1 more source