Results 41 to 50 of about 29,219 (267)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Communication, Technology, Temporality

open access: yescommunication +1, 2012
This paper proposes a media studies that foregrounds technological objects as communicative and historical agents. Specifically, I take the digital computer as a powerful catalyst of crises in communication theories and certain key features of modernity.
Mark A. Martinez
doaj   +1 more source

La temporalidad en los manuales de Historia Antigua: de Astolfi a los manuales del siglo XXI

open access: yesClio y Asociados, 2020
This article collects the main guidelines of our master's thesis in Specific Didactics, at the Universidad Nacional delLitoral, entitled ‘The teaching of the temporal dimension in Ancient history textbooks.
María Silvia Álvarez
doaj   +1 more source

Temporality of Subjective Information

open access: yesComputer Sciences & Mathematics Forum, 2023
What philosophy truly needs is to re-present the problems of the relationship between the natural world and consciousness, matter and spirit at a higher and deeper theoretical level.
Yaru Chen, Kun Wu
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Making Time for Critique: Canadian ‘Right to Shelter’ Debates in a Chrono-Political Frame

open access: yesThe Windsor Yearbook of Access to Justice, 2020
This article engages with Canadian ‘right to shelter’ discourse, with a focus on shared assumptions that do crucial work but are sometimes unstated.
Mark Zion
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Temporality in Heidegger’s Early Thought [PDF]

open access: yesJournal of Philosophical Investigations, 2019
For the establishment of the fundamental ontology, early Heidegger disregards the vulgar understanding of time and analyzes temporality. He believes that the vulgar understanding of time is the degeneration of the world-time, and the world-time itself is
Ehsan Nazari, Seyed Masoud Sayf
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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