Results 51 to 60 of about 80,704 (296)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Book review of Temporal Urban Design – Temporality, Rhythm and Place
Book review of Temporal Urban Design – Temporality, Rhythm and Place (Author Filipa Matos Wunderlich, Publisher: Routledge, Year of publication: 2024, ISBN: 978-1-4724-6870-3) for Urban Design ...
Kamvasinou, K.
core +3 more sources
Effects of network temporality on coevolution spread epidemics in higher-order network
Journal of King Saud University: Computer and Information Sciences, 2022 Interactions between people, including pairwise and higher-order interactions, can be approximated as temporal higher-order networks, where the connections are constantly created and broken over time.
Yanyi Nie +5 more
doaj +1 more source
Semantics of temporal queries and temporal data [PDF]
Proceedings of the 23rd annual meeting on Association for Computational Linguistics -, 1985 This paper analyzes the requirements for adding a temporal reasoning component to a natural language database query system, and proposes a computational model that satisfies those requirements. A preliminary implementation in Prolog is used to generate examples of the model's capabilities.
openaire +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Communication, Technology, Temporality
communication +1, 2012 This paper proposes a media studies that foregrounds technological objects as communicative and historical agents. Specifically, I take the digital computer as a powerful catalyst of crises in communication theories and certain key features of modernity.
Mark A. Martinez
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
La temporalidad en los manuales de Historia Antigua: de Astolfi a los manuales del siglo XXI
Clio y Asociados, 2020 This article collects the main guidelines of our master's thesis in Specific Didactics, at the Universidad Nacional delLitoral, entitled ‘The teaching of the temporal dimension in Ancient history textbooks.
María Silvia Álvarez
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source