Results 101 to 110 of about 611,786 (340)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

The Work of Art and Truth of Being as Historical : Reading Being and Time, The Origin of the Work of Art, and the Turn (Kehre) in Heidegger’s Philosophy of the 1930s [PDF]

open access: yes, 2009
Reading Heidegger’s Being and Time, “The Origin of the Work of Art,” and the 1934-35 lecture courses Hölderlin’s Hymns“Germania” and “The Rhine,” the aim of this essay is twofold. First, the essay attempts to elucidate the manner in which the work of art
Magrini, James
core   +1 more source

Sartre's Postcartesian Ontology: On Negation and Existence [PDF]

open access: yes, 2009
This article maintains that Jean-Paul Sartre’s early masterwork, Being and Nothingness, is primarily concerned with developing an original approach to the being of consciousness. Sartre’s ontology resituates the Cartesian cogito
Arthur C. Danto   +17 more
core   +1 more source

L’apport des neurosciences au modèle de l’Identité-Logement : Les stratégies d’apprentissage des personnes âgées concernées par la chute

open access: yesÉducation et Socialisation, 2018
Prevention of falls among the elderly, supported by home improvement strategies and changes in habits, raises the issue of learning. The concept of home-identity links the learning strategies of the elderly inhabitant with his or her temporality and ...
Frédérique TRÉVIDY   +2 more
doaj   +1 more source

TEMPORAL NATURALISM

open access: yesStudies in History and Philosophy of Science Part B: Studies in History and Philosophy of Modern Physics, 2015
Two people may claim both to be naturalists, but have divergent conceptions of basic elements of the natural world which lead them to mean different things when they talk about laws of nature, or states, or the role of mathematics in physics. These disagreements do not much affect the ordinary practice of science which is about small subsystems of the ...
openaire   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

The systemic mind and a conceptual framework for the psychosocial environment of business enterprises: Practical implications for systemic leadership training [PDF]

open access: yes, 2015
This chapter introduces a research-based conceptual framework for the study of the inner psychosocial reality of business enterprises. It is called the Inner Organizational Ecosystem Approach (IOEA).
Parma, Petr, Trnka, Radek
core  

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

Museum temporality

open access: yesШаги
A review of: Walklate, J. (2023). Time and the museum: Literature, phenomenology, and the production of radical temporality. Routledge. 210 p.
V. K. Karnaukh
doaj  

No Time to Queer. The Reception of Queer Temporalities in Germany

open access: yesOpen Gender Journal
Queer Temporality Studies have been one of the most productive fields within US-American queer theory over the last two decades. In Germany, the temporal turn in criticism has also led to a lot of academic discussion around the topics of time and ...
Felix Schmidt
doaj   +1 more source

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