Results 51 to 60 of about 1,310,512 (352)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Politics, public servants, and profits: Institutional complexity and temporary hybridization in a public infrastructure alliance project

open access: yesInternational Journal of Project Management, 2019
Public infrastructure projects must comply with the divergent and even conflicting demands of multiple institutional logics causing institutional complexity.
Juri Matinheikki, K. Aaltonen, D. Walker
semanticscholar   +1 more source

A Review of Temporary Housing Management Modeling: Trends in Design Strategies, Optimization Models, and Decision-Making Methods

open access: yesSustainability, 2020
Temporary housing plays a critical role in disaster response and recovery by providing a temporary home for displaced people before they return to their permanent residence.
Daniel Perrucci, H. Baroud
semanticscholar   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Development Impacts of Seasonal and Temporary Migration: A Review of Evidence from the Pacific and Southeast Asia [PDF]

open access: yes, 2013
Seasonal and temporary migration programs are widely used around the world, yet there is scant evidence as to their development impacts. Absent such evidence, it is difficult to evaluate whether the proliferation of temporary worker programs in recent ...
John Gibson   +6 more
core   +1 more source

Temporary Migration and Climate Variation in Eastern Africa

open access: yesWorld Development, 2019
Africa is likely to experience warming and increased climate variability by the late 21st century. Climate extremes have been linked to adverse economic outcomes.
V. Mueller   +3 more
semanticscholar   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

The connection between classroom climate and emotions in educational context and their relationship with academic achievement

open access: yesInovacije u Nastavi
Based on Pekrun’s control-value theory, this paper examines the relationship between academic emotions and classroom climate. The aim of the research is to investigate the connection between classroom climate and emotions in teaching, as well as their ...
Dušan J. Ranđelović   +1 more
doaj   +1 more source

Transient Voice Loss after Spinal Anaesthesia for Lower Limb Surgery: A Case Report [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Spinal Anaesthesia (SA) with hyperbaric bupivacaine and opioids is a preferred technique for lower limb surgeries in many centres. Among the various complications of such anaesthesia, postprocedural voice loss is relatively uncommon and has been reported
Navneeta Bisht, Gaurav Misra
doaj   +1 more source

Temporary Jobs: Stepping Stones or Dead Ends?

open access: yesSocial Science Research Network, 2002
In Britain about 7% of male employees and 10% of female employees are in temporary jobs. In contrast to much of continental Europe, this proportion has been relatively stable over the 1990s.
Alison L. Booth   +2 more
semanticscholar   +1 more source

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