Results 31 to 40 of about 681,716 (312)
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Based on Pekrun’s control-value theory, this paper examines the relationship between academic emotions and classroom climate. The aim of the research is to investigate the connection between classroom climate and emotions in teaching, as well as their ...
Dušan J. Ranđelović +1 more
doaj +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Context: This study compared the accuracy of computer-aided design and computer-aided manufacturing (CAD/CAM) milled temporary dental crowns using Metrology software.
Rajesh Suhas Swami, Sayed M. Killedar
doaj +1 more source
Objective: To compare the health-related quality of life (HRQOL) between colorectal cancer (CRC) patients with temporary and permanent stoma. Methods: This survey was a cross-sectional study that was conducted on 110 CRC patients living with stoma.
Natharom Chutikamo, R.N. +2 more
doaj +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Effect of different polishing methods on surface roughness of provisional prosthetic materials
Purpose: To evaluate the surface roughness of bis-acrylic and acrylic resins submitted to different methods of polishing. Materials and Methods: Fifty samples of each provisional restorative material (Structur 2, Protemp 4, Duralay, and Dencrilay) were ...
Ivian Verena Maia Tupinamba +3 more
doaj +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source

