Results 41 to 50 of about 12,394 (222)

Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells

Journal of Functional Biomaterials, 2023
Temporomandibular disorder (TMD) is an umbrella term used to describe various conditions that affect temporomandibular joints, masticatory muscles, and associated structures. Although the most conservative and least invasive treatment is preferable, more
Zuleni Alexandre da Silva, Wallacy Watson Pereira Melo, Hadassa Helez Neves Ferreira, Rafael Rodrigues Lima, Renata Duarte Souza-Rodrigues   +4 more
doaj   +1 more source

Detection and Severity Assessment of Temporomandibular Joint Osteoarthritic Changes in Patients with Temporomandibular Disorders Using CBCT

Erbil Dental Journal
Background and objectives: Osteoarthritis refers to a non-inflammatory condition often linked to aging. It involves the gradual breakdown of bone, cartilage, and surrounding soft tissues around the joints.
Kharman Khidhr Rahman, Shahen Ali Ahmed, Sarkawt Hamad Ali, Khoshee Salh Hamed   +3 more
doaj   +1 more source

Quantification of condylar resorption in temporomandibular joint osteoarthritis [PDF]

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2010
This study was performed to determine the condylar morphologic variation of osteoarthritic (OA) and asymptomatic temporomandibular joints (TMJs) and to determine its correlation with pain intensity and duration.Three-dimensional surface models of mandibular condyles were constructed from cone-beam computerized tomography images of 29 female patients ...
L H S, Cevidanes, A-K, Hajati, B, Paniagua, P F, Lim, D G, Walker, G, Palconet, A G, Nackley, M, Styner, J B, Ludlow, H, Zhu, C, Phillips   +10 more
openaire   +2 more sources

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Matrix Metalloproteinases and Temporomandibular Joint Disorder: A Review of the Literature [PDF]

, 2019
Temporomandibular disorders (TMD) are progressive degenerative disorders that affect the components of the temporomandibular joint (TMJ), characterized by pain and limitations in function.
Almeida, Luis Eduardo, Camejo, Flavio, Haxhia, Ardit, Herm, Logan, Tayebi, Lobat   +4 more
core   +1 more source

Development of temporomandibular joint arthritis: the use of animal models [PDF]

, 2017
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Ghassemi-Nejad, Sheida, Kobezda, Tamás, Szekanecz, Zoltán, Tar, Ildikó   +3 more
core   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

The petrotympanic canal (Huguier canal): Evolutionary, anatomical, and medical perspectives

The Anatomical Record, EarlyView.
Abstract The petrotympanic canal, traditionally referred to as Civinini's or Huguier's canal, represents an anatomical passage connecting the middle ear and temporomandibular joint (TMJ). Despite its early description, its structural complexity and functional significance have often been underestimated. In this study, we combined historical, anatomical,
Andrea Papini, Nicola Montemurro, Ferdinando Paternostro, Immacolata Belviso, Massimo Galli, Petra Martini, Licia Uccelli, Jacopo Moggi‐Cecchi, Gregorio Oxilia   +8 more
wiley   +1 more source

Comorbidities in aging patients with sickle cell disease. [PDF]

, 2018
Sickle cell disease (SCD) in general and sickle cell anemia in particular is a highly complex disorder both at the molecular and clinical levels. Although the molecular lesion is a single-point mutation, the sickle gene is pleiotropic in nature causing ...
Ballas, Samir K.
core   +2 more sources

Sel1l preserves condylar cartilage matrix homeostasis by regulating PERK signaling

Interdisciplinary Medicine, EarlyView.
Our study revealed that the expression of Sel1l was downregulated in OA cartilage and that Sel1l deficiency induced cartilage catabolism. Mechanistically, Sel1l depletion aberrantly activated PERK signaling and resulted in ER stress. PERK inhibition rescued the phenotype of Sel1l‐deficient chondrocytes and alleviated TMJOA pathogenesis.
Xinqi Huang, Zinan Cen, Zhihe Zhao, Xiao Cen   +3 more
wiley   +1 more source