Results 21 to 30 of about 173,609 (238)
Pediatric Blood &Cancer, EarlyView.Abstract Background Sickle cell disease (SCD) is an autosomal recessive hemoglobinopathy affecting millions of individuals worldwide. The clinical expression and psychosocial burden of SCD vary widely across geographical, cultural, and healthcare system contexts, underscoring the need for setting‐specific approaches to assessment.
Desiré Fantasia +7 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Hemoglobinopathies are prevalent globally; diagnosis is complex in high genetic admixture populations like Brazil. We report, in two pediatric siblings, the first documented cases in Brazil of heterozygosity for hemoglobin (Hb) O‐Arab with coinheritance of α‐thalassemia (αα/−α4.2; −α3.7/−α4.2), resulting in microcytic and hypochromic anemia ...
Elisângela de Souza Miranda Muynarsk +9 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa +3 more
wiley +1 more source
Una revisió de les tendències contemporànies en avaluació en l'educació superior
@tic: Revista d'Innovació Educativa, 2015 L’avaluació en té un gran importància, i contribueix significativament a l'aprenentatge dels estudiants, especialment quan està dissenyada per a ser adequada al seu propòsit, quan és autèntica i està centrada en la integració de l’avaluació amb l ...
Sally Brown
doaj +1 more source
Noves tendències del disseny interactiu [PDF]
, 2004 Moltes gràcies per donar-me aquesta oportunitat de parlar sobre les noves tendències del disseny interactiu digital. He dividit la presentació en tres tendències: . del monitor al món real . de la complexitat a la simplicitat .
Scolari, Carlos Alberto
core
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Les tendències del sector farmacèutic [PDF]
, 2012 La influència de la genètica en els nous ...
Juan J. Estruch
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
De l'«economia informal» a «formes de treball»: models i tendències transnacionals
Papers, 1990 En aquest article Pahl aposta per una investigació transnacional i comparativa de I'economia informal, que decididament prefereix anomenar formes de treball informal, ja que aquest és un concepte més precís i capaç d'englobar des del treball dit negre ...
R. E. Pahl
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source