Results 31 to 40 of about 148,561 (189)

Revistes d'accés obert : característiques, models econòmics i tendències

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2008
Existeixen exemples de revistes electròniques científiques d'accés obert (OA) des de l'aparició d'Internet. Tanmateix, amb la Declaració de Budapest, en la qual es defineix el significat d'accés obert i les revistes com una via per assolir-lo, comencen a
Melero, Remedios   +1 more
doaj  

Evolució i tendències en l'ocupació del sòl a les illes balears

open access: yesCuadernos de Geografía de la Universitat de València
This study analyses the changes in land use in the Balearic Islands during the 1956-2000 period and the growth potential generated by the planning policy, while examining the industrial and urban coverage of land caused by the tourism and real estate ...
Ivan Murray   +2 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Kingdom: un teatre postdramàtic polític?

open access: yes452ºF, 2020
A propòsit de l’obra teatral Kingdom (2018), de l’Agrupación Señor Serrano, repassarem el conflicte que obre Hans Thies Lehmann respecte la pertinença actual del teatre polític. Primerament proposarem una definició operativa de «teatre polític», tant des
Marta Duran Arranz
doaj  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Espais de consum i activacions transmèdia

open access: yesTemes de Disseny, 2017
Els espais de consum es veuen obligats a preveure i a satisfer les necessitats i els desitjos dels seus clients i, per tant, han d'estar sempre pendents de les principals macrotendències imperants en el sector.
doaj  

Tendències innovadores en l'Administració pública i el dret administratiu italià

open access: yesRevista Catalana de Dret Públic, 1992
.
Domenico Sorace
doaj  

Home - About - Disclaimer - Privacy