Results 81 to 90 of about 173,609 (238)

Tendències en l'alimentació : Alimentària 2006 [PDF]

, 2006
Actualment, l'alimentació ofereix als consumidors moltes més opcions que fa uns anys. Aquesta ràpida evolució respon a la necessitat d'adaptació d'aquest sector al trepidant ritme de vida que pateix la nostra societat.
Arranz Iglesias, Laura Isabel, Castells Cuixart, Marta   +1 more
core  

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

High anxiety levels are associated with divergent empathising and systemising tendencies

Cogent Psychology, 2014
“Systemising” and “Empathising” are two cognitive tendencies that individuals rely on to make sense of the world. Systemising involves the observation of environmental contingencies and the consequent formulation of concrete rules to predict events ...
Paul A. Strutt, Linda Elisabet Campbell, Darren Burke   +2 more
doaj   +1 more source

Més enllà i més ençà del relativisme: tres filòsofs postmoderns i les seues raòns [PDF]

, 2009
Les diferents filosofies “postmodernes” que sorgiren dels anys 1970 als anys 1990 s'han considerat sovint com una classe d´“ideología” irracionalista-escèptica-relativista (o alguna altra sort d´amalgama semblant) que en el nostre temps prendrien ...
Paz, Miguel Angel Quintana
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

La necessària adaptació dels tributs a les noves tendències dels negocis electrònics

IDP, 2014
Agència Estatal d'Administració TributàriaEls nous models de negoci digitals i la complexitat d'algunes operacions de comerç electrònic troben a la xarxa el nínxol idoni per a la derivació dels beneficis cap a territoris en els quals hi ha una menor o ...
Bartolomé Borrego Zabala
doaj  

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source