Results 51 to 60 of about 62,717 (282)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Flexible Smart Energy-Management Systems Using an Online Tendering Process Framework for Microgrids
Energies, 2023 Currently, modern power grids are evolving into complex cyber-physical systems integrated with distributed energy resources that can be controlled and monitored by computer-based algorithms.
Mansour Selseleh Jonban +3 more
doaj +1 more source
The optimisation of a strategic business process [PDF]
, 2003 The optimisation of a Tendering Process for Warship Refit Contracts is presented. The Pre Contract Award process (PCA) involves all the activities needed to successfully win a Refit Contract, e.g. estimating, planning, tendering and negotiation.
Ball, P.D. +3 more
core
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Experience of switching to NovoEight: views of people with haemophilia
The Journal of Haemophilia Practice, 2020 Management of haemophilia A requires administration of factor VIII therapy which, for those with severe haemophilia A in the UK, is predominantly self-administered at home in a prophylactic regimen to prevent or minimise bleeding.
Pollard Debra, Khair Kate, Holland Mike
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Norwegian experiences with tendered buss services [PDF]
, 2006 Competitive tendering of local public transport services has been allowed in Norway since 1994. By 2005, 28 percent of all route production in Norway was procured on the basis of tendered contracts, covering around 40 percent of all passengers.
Bekken, Jon-Terje +3 more
core +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Library purchasing consortia: the UK periodicals supply market [PDF]
, 2000 This article is based on surveys undertaken for a British Library Research and Innovation Centre/Library and Information Commission-funded research project.
Ball, David, Pye, Jo
core +1 more source