Results 61 to 70 of about 12,393 (286)

Security and legal issues in E-tendering [PDF]

open access: yes, 2005
The Queensland Department of Public Works (QDPW) and the Queensland Department of Main Roads (QDMR) have identified a need for industry e-contracting guidelines in the short to medium term.
Christensen, Sharon   +7 more
core   +1 more source

Contractual Obligations in the Pre-Award Phase of Public Tendering

open access: yesOsgoode Hall Law Journal, 1998
The law of public tendering has received vigorous scrutiny since the Supreme Court of Canada's landmark decision in R. v. Ron Engineering. The Supreme Court's two-contract model re-defined the juristic boundaries of the tendering process, imposing a ...
Peter Devonshire
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

The impact of compulsory competitive tendering on refuse collection services [PDF]

open access: yes
Compulsory competitive tendering (CCT) of blue-collar services such as refuse collection and street cleaning was introduced in the UK by the Local Government Act 1988.
Stefan Szymanski
core  

LEGAL PROTECTION OF THE DEBTOR CONSTRUCTION COMPLETION OF NONPERFORMING LOANS BY AUCTION OF LIABILITY WARRANTIES

open access: yesJurnal Pembaharuan Hukum, 2018
The resolutions of non-performing loans with tendering guarantee Encumbrance Often bring up the resistance of the debtor in the form of Civil Lawsuit filed to the District Court the which is due to the complexity of the auction and Several weaknesses ...
Lusia Sulastri
doaj   +1 more source

Secure Tender -A Blockchain Tendering System

open access: yes
This project delivers a rapid digital transformation in procurement processes has increased the need for secure, transparent, and efficient systems. Traditional e-tendering solutions face issues such as data manipulation, lack of transparency, and inefficiency.
Karrem Usha   +3 more
openaire   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

“To Bid or Not to Bid, This is the Question: The Italian Experience in Competitive Tendering for Local Bus Services” [PDF]

open access: yes
Competitive tendering is a popular mechanism for the provision of local bus services when a major objective is subsidy savings. Despite uncertainties in the legal rules some competitive tendering was implemented in Italy since 1998.
Boitani, Andrea, Cambini, Carlo
core  

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