Results 51 to 60 of about 12,393 (286)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Procurement challenges analysis of Iraqi construction projects
Journal of the Mechanical Behavior of Materials, 2022 Public procurement in Iraq plays an essential function in the development and recovery of the country's economy as well as providing the essential infrastructure for the growth of the private sector.
Hamza Sadeq Abdul +2 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
First interim report : cost of tendering [PDF]
, 2008 This is the first interim report on the Cost of Tendering component of the Best Value project. This report provides some insight from ‘cost of tendering’ literature and\ud discussions with CRC partners.\ud With the completion of this scoping project ...
core
The application of post tender negotiation procedure: a public sector procurement perspective in UK
International Journal of Information Systems and Project Management, 2016 0
Peter Manso, Athanasios Nikas, , ,
doaj +1 more source
The Influencing Factors of Smes Participation in Public Procurement [PDF]
Ovidius University Annals: Economic Sciences Series, 2022 The paper proposes an analysis of the success factors of SMEs in the award of contracts based on public procurement. Research results have shown that SMEs to win contracts through public tenders increases significantly if more attention is paid to tender
Ecaterina Milica Dobrotă +2 more
doaj
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Tendering procedures, contractual arrangements and Latham: The contractors' view
, 1996 The procedural and administrative aspects of UK tendering have remained largely unaltered for decades but this may soon change in light of the recent review of the construction sector, headed by Sir Michael Latham.
Olomolaiye, Paul +3 more
core +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source