Results 11 to 20 of about 45,529 (309)

Animal model for tendinopathy

open access: yesJournal of Orthopaedic Translation, 2023
Background: Tendinopathy is a common motor system disease that leads to pain and reduced function. Despite its prevalence, our mechanistic understanding is incomplete, leading to limited efficacy of treatment options.
Junchao Luo   +14 more
doaj   +3 more sources

Tendinopathy of tendo Achillis [PDF]

open access: bronzeThe Journal of Bone and Joint Surgery. British volume, 2002
study, however, 31% of 58 patients with this condition did not participate in vigorous physical activity. 3 In this article, we have concentrated on tendinopathy of the main body of tendo Achillis. We have not dealt with Haglund's condition, insertional tendinopathy, or with lesions of the myotendinous junction. Anatomy. The gastrocnemius muscle merges
Nicola Maffulli, Deiary F. Kader
openalex   +7 more sources

Neuropeptides in tendinopathy [PDF]

open access: bronzeFrontiers in Bioscience, 2009
Overuse tendinopathy remains a major clinical burden for sports medicine and general practitioners. Recent studies have highlighted the role of sensory and autonomic nerves in generating or perpetuating the symptoms and tissue abnormalities associated with tendinopathy.
Alex Scott
openalex   +5 more sources

Parishin A-loaded mesoporous silica nanoparticles modulate macrophage polarization to attenuate tendinopathy

open access: yesnpj Regenerative Medicine, 2023
Macrophages are involved mainly in the balance between inflammation and tenogenesis during the healing process of tendinopathy. However, etiological therapeutic strategies to efficiently treat tendinopathy by modulating macrophage state are still lacking.
Lisha Zhu   +13 more
semanticscholar   +1 more source

Biopsychosocial approach to tendinopathy [PDF]

open access: yesBMJ Open Sport & Exercise Medicine, 2022
Tendinopathy describes a spectrum of changes that occur in damaged tendons, leading to pain and reduced function that remains extremely challenging for all clinicians. There is an increasing awareness of the influence that psychological and psychosocial components, such as self-efficacy and fear-avoidance, have on rehabilitation outcomes in ...
Nathan Edgar   +5 more
openaire   +3 more sources

Inhibition of Integrin αvβ6 Activation of TGF‐β Attenuates Tendinopathy

open access: yesAdvanced Science, 2022
Tendinopathy is a common tendon disorder that causes pain and impairs function. It is the most common reason for consultation with musculoskeletal specialists.
Xiao Wang   +11 more
doaj   +1 more source

Roles of Oxidative Stress in Acute Tendon Injury and Degenerative Tendinopathy—A Target for Intervention

open access: yesInternational Journal of Molecular Sciences, 2022
Both acute and chronic tendon injuries are disabling sports medicine problems with no effective treatment at present. Sustained oxidative stress has been suggested as the major factor contributing to fibrosis and adhesion after acute tendon injury as ...
P. Lui   +4 more
semanticscholar   +1 more source

Nearly half of patients with chronic tendinopathy may have a neuropathic pain component, with significant differences seen between different tendon sites: a prospective cohort of more than 300 patients

open access: yesBMJ Open Sport & Exercise Medicine, 2022
Objectives Identifying the prevalence of neuropathic pain components in patients with chronic tendinopathy conditions using the Self-Administered Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS) questionnaire.Methods Patients with chronic ...
Patrick C Wheeler
doaj   +1 more source

Clinical Association of Achilles Tendinopathy and Hypertension Mediated by CaV1.2 Voltage-gated Ca2+ Channel

open access: yesFoot & Ankle Orthopaedics, 2023
Category: Basic Sciences/Biologics; Hindfoot Introduction/Purpose: The Achilles tendon is subject to acute- and overuse-injuries, which may result in degenerative tendinopathy.
David J. Ciufo MD   +3 more
doaj   +1 more source

Metalloproteases and tendinopathy [PDF]

open access: yesMuscle Ligaments and Tendons Journal, 2013
Matrix metalloproteinases (MMP) are involved in the development of tendinopathy. These potent enzymes completely degrade all components of the connective tissue, modify the extracellular matrix (ECM), and mediate the development of painful tendinopathy.
Nicola Maffulli   +4 more
openaire   +7 more sources

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