Results 21 to 30 of about 34,054 (265)

The Implication of Substance P in the Development of Tendinopathy: A Case Control Study. [PDF]

, 2017
It was reported that substance P had beneficial effects in the healing of acute tendon injury. However, the relationship between substance P and degenerative tendinopathy development remains unclear. The purpose of this study was to determine the role of
Ahn, Heejung, Ahn, Taekeun, Baik, Lloyd, Byun, Seong-Eun, Choi, Wonchul, Choi, Youngrak, Ding, Catherine, Han, Soo-Hong, Kim, Jaehee, Lee, Seungyong, Lee, Soonchul, Song, Jiye, Ting, Kang, Ward, Spencer   +13 more
core   +1 more source

Determining minimal important differences for patient-reported outcome measures in shoulder, lateral elbow, patellar and Achilles tendinopathies using distribution-based methods

BMC Musculoskeletal Disorders, 2023
Background Minimal important difference (MID) is a concept used inconsistently and arbitrarily in tendinopathy research. Our aim was to determine the MIDs for the most commonly used tendinopathy outcome measures using data-driven approaches.
Dimitris Challoumas, Andrea Zouvani, Kevin Creavin, Elspeth Murray, Gearoid Crosbie, Nigel Ng, Neal L. Millar   +6 more
doaj   +1 more source

The pathogenesis of tendinopathy. A molecular perspective [PDF]

, 2004
There are many publications that discuss the aetiology, diagnosis and treatment of the various forms of tendinopathy, but few are based on conclusive scientific evidence.
Riley, GP
core   +1 more source

Increased expression of glutathione peroxidase 3 prevents tendinopathy by suppressing oxidative stress

Frontiers in Pharmacology, 2023
Tendinopathy, a degenerative disease, is characterized by pain, loss of tendon strength, or rupture. Previous studies have identified multiple risk factors for tendinopathy, including aging and fluoroquinolone use; however, its therapeutic target remains
Haruka Furuta, Mari Yamada, Takuya Nagashima, Shuichi Matsuda, Kazuki Nagayasu, Hisashi Shirakawa, Shuji Kaneko   +6 more
doaj   +1 more source

Variants within the MMP3 gene are associated with achilles tendinopathy: possible interaction with the COL5A1 gene [PDF]

, 2009
Objectives: Sequence variation within the COL5A1 and TNC genes are known to associate with Achilles tendinopathy. The primary aim of this case-control genetic association study was to investigate whether variants within the matrix metalloproteinase 3 ...
Collins, M, Raleigh, Stuart M, Ribbans, William J, Schwellnus, M P, Smith, R K, van der Merwe, L   +5 more
core   +1 more source

Targeting danger molecules in tendinopathy: the HMGB1/TLR4 axis [PDF]

, 2017
Objectives: To seek evidence of the danger molecule, high-mobility group protein B1 (HMGB1) expression in human tendinopathy and thereafter, to explore mechanisms where HMGB1 may regulate inflammatory mediators and matrix regulation in human tendinopathy.
Akbar, Moeed, Crowe, Lindsay A.N., Garcia-Melchor, Emma, Gilchrist, Derek S., Kerr, Shauna C., Kitson, Susan M., McInnes, Iain B., Millar, Neal L., Murrell, George A.C., Nelis, Briana, Reilly, James H.   +10 more
core   +1 more source

IL-21 receptor expression in human tendinopathy [PDF]

, 2014
The pathogenetic mechanisms underlying tendinopathy remain unclear, with much debate as to whether inflammation or degradation has the prominent role.
Campbell, Abigail L., Fazzi, Umberto G., Kerr, Shauna C., Leach, William J., Millar, Neal L., Murrell, George A.C., Reilly, James H., Rooney, Brian P., Smith, Nicola C.   +8 more
core   +2 more sources

Therapeutic Roles of Tendon Stem/Progenitor Cells in Tendinopathy

Stem Cells International, 2016
Tendinopathy is a tendon disorder characterized by activity-related pain, local edema, focal tenderness to palpation, and decreased strength in the affected area.
Xin Zhang, Yu-cheng Lin, Yun-feng Rui, Hong-liang Xu, Hui Chen, Chen Wang, Gao-jun Teng   +6 more
doaj   +1 more source

Gene expression and matrix turnover in overused and damaged tendons [PDF]

, 2005
Chronic, painful conditions affecting tendons, frequently known as tendinopathy, are very common types of sporting injury. The tendon extracellular matrix is substantially altered in tendinopathy, and these changes are thought to precede and underlie the
Abbaszade I, Akeson WH, Alfredson H, Amiel D, Archambault J, Astrom M, Bank RA, Banyard J, Benjamin M., Berenson MC, Boot-Handford RP, Brown PD., Cal S, Caterson B, Cawston TE, Cawston TE., Clark IM, Colige A, Colige A, Collins-Racie LA, Corps AN, Corps AN, Curwin SL, Dalton S, Dickinson SC, Eriksen HA, Everts V, Fernandes RJ, Fitzgerald J, Flannery CR, G. P. Riley, Gao G, Gelberman RH, Gillard GC, Gotoh M, Hannafin JA., Hardingham TE, Hashimoto T, Heinemeier K, Ireland D, Jarvinen M, Jozsa L, Jozsa L, Kannus P, Kannus P., Kannus P., Kashiwagi M, Kashiwagi M, Kaushal GP, Kjaer M, Koch M, Koch M, Koshy PJ, Koskinen SO, Kuno K, Langberg H, Langberg H, Langberg H, Leadbetter WB., Lehto M, McCawley LJ, McNeilly CM, Murphy G, Myllyharju J, Nagase H., Pace JM, Patterson-Kane JC, Pierfitte C, Rees SG, Riley G., Riley GP, Riley GP, Riley GP, Riley GP, Riley GP, Riley GP., Samiric T, Samiric T, Sandy JD, Sandy JD, Sandy JD, Sato K, Smith RK, Smith RK, Somerville RP, Tipton CM, Tortorella MD, Tortorella MD, Tsuzaki M, Vankemmelbeke MN, Vogel KG, Waggett AD, Wang P, Woo SLY, Woo SLY, Woo SLY, Yasuda K, Yoshihara Y   +97 more
core   +1 more source

Prevalence, risk factors and treatment outcomes of fluoroquinolones-associated tendinopathy in tuberculosis patients at university hospital, Thailand

Heliyon, 2023
Background: Tuberculosis (TB) is an epidemic disease in Thailand. Fluoroquinolones are used to treat TB and have a lengthy treatment course. Therefore, many patients may have adverse effects from these medications.
Jirarat Chongboonwatana, Varalee Terbsiri, Gompol Suwanpimolkul   +2 more
doaj