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The vasculature and its role in the damaged and healing tendon [PDF]
, 2002 Tendon pathology has many manifestations, from spontaneous rupture to chronic tendinitis or tendinosis; the etiology and pathology of each are very different, and poorly understood. Tendon is a comparatively poorly vascularised tissue that relies heavily
Fenwick, SA, Hazleman, BL, Riley, GP
core +2 more sources
Tendon proper- and peritenon-derived progenitor cells have unique tenogenic properties. [PDF]
, 2014 IntroductionMultipotent progenitor populations exist within the tendon proper and peritenon of the Achilles tendon. Progenitor populations derived from the tendon proper and peritenon are enriched with distinct cell types that are distinguished by ...
Adams, Sheila M +2 more
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The Regulation of Aggrecanase ADAMTS-4 Expression in Human Achilles Tendon and tendon-Derived Cells [PDF]
, 2008 Several members of the ADAMTS (A Disintegrin And Metalloproteinase with ThromboSpondin motifs) family have been identified as aggrecanases, whose substrates include versican, the principal large proteoglycan in the tendon extracellular matrix.
Corps, Anthony N. +5 more
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BMC Musculoskeletal Disorders, 2018 Background Fibroblast behavior and cell-matrix interactions of cells from normal and idiopathic carpal tunnel syndrome (CTS) subsynovial connective tissue (SSCT) with and without Triamcinolone Acetonide (TA) were compared in this study. A cell-seeded gel
Tai-Hua Yang +5 more
doaj +1 more source
How does a cadaver model work for testing ultrasound diagnostic capability for rheumatic-like tendon damage? [PDF]
, 2016 To establish whether a cadaver model can serve as an effective surrogate for the detection of tendon damage characteristic of rheumatoid arthritis (RA). In addition, we evaluated intraobserver and interobserver agreement in the grading of RA-like tendon ...
A Iagnocco +42 more
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Biology of Tendon Stem Cells and Tendon in Aging [PDF]
Frontiers in Genetics, 2020 Both tendon injuries and tendinopathies, particularly rotator cuff tears, increase with tendon aging. Tendon stem cells play important roles in promoting tendon growth, maintenance, and repair. Aged tendons show a decline in regenerative potential coupled with a loss of stem cell function.
Lui, PPY, Wong, CM
openaire +5 more sources
Sex variation in patellar tendon kinetics during running [PDF]
, 2015 Purpose. The aim of the current investigation was to determine whether female recreational runners exhibit distinct patellar tendon loading patterns in relation to their male counterparts. Methods.
Almekinders +23 more
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Non-viral Gene Delivery Methods for Bone and Joints
Frontiers in Bioengineering and Biotechnology, 2020 Viral carrier transport efficiency of gene delivery is high, depending on the type of vector. However, viral delivery poses significant safety concerns such as inefficient/unpredictable reprogramming outcomes, genomic integration, as well as unwarranted ...
Benjamin Gantenbein +10 more
doaj +1 more source
Cells, 2019 Tendinopathy is accompanied by a cascade of inflammatory events promoting tendon degeneration. Among various cytokines, interleukin-1β plays a central role in driving catabolic processes, ultimately resulting in the activation of matrix ...
Renate Gehwolf +8 more
doaj +1 more source