Results 81 to 90 of about 549,658 (409)

Engineering Musculoskeletal Grafts for Multi-Tissue Unit Repair: Lessons From Developmental Biology and Wound Healing

open access: yesFrontiers in Physiology, 2021
In the musculoskeletal system, bone, tendon, and skeletal muscle integrate and act coordinately as a single multi-tissue unit to facilitate body movement.
Xu Zhang   +12 more
doaj   +1 more source

Effect of front and back squat techniques on peak loads experienced by the Achilles tendon [PDF]

open access: yes, 2015
Background A primary technique in the discipline of strength and conditioning the squat has two principal ‘back and front’ variants. Despite the physiological and strength benefits of the squat, the propensity for musculoskeletal injury is high.
Atkins, Stephen   +4 more
core  

The pathogenesis of tendinopathy. A molecular perspective [PDF]

open access: yes, 2004
There are many publications that discuss the aetiology, diagnosis and treatment of the various forms of tendinopathy, but few are based on conclusive scientific evidence.
Riley, GP
core   +1 more source

Anionic Citrate‐Based 3D‐Printed Scaffolds for Tunable and Sustained Orthobiologic Delivery to Enhance Tissue Regeneration

open access: yesAdvanced Functional Materials, EarlyView.
A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee   +12 more
wiley   +1 more source

Tendon injuries

open access: yesEFORT Open Reviews, 2017
Tendons connect muscles to bones, ensuring joint movement. With advanced age, tendons become more prone to degeneration followed by injuries. Tendon repair often requires lengthy periods of rehabilitation, especially in elderly patients. Existing medical
Fan Wu, M. Nerlich, D. Docheva
semanticscholar   +1 more source

HGF Mediates the Anti-inflammatory Effects of PRP on Injured Tendons [PDF]

open access: yes, 2013
Platelet-rich plasma (PRP) containing hepatocyte growth factor (HGF) and other growth factors are widely used in orthopaedic/sports medicine to repair injured tendons.
A Mishra   +61 more
core   +1 more source

Soft Pneumatic Device Designed to Mimic the Periosteal Environment for Regulating the Fate of Mesenchymal Stem Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a custom‐made soft pneumatic device (SPD) that mimics complex mechanical forces and fluid flow to enhance in vitro cell differentiation. It shows that low mechanotransduction promotes MSC differentiation into osteoprogenitor cells, while high mechanotransduction causes structural disruptions and cell detachment, providing new ...
Gwang‐Bum Im   +9 more
wiley   +1 more source

Noninvasive magnetic resonance-guided focused ultrasound for tendon disruption: an in vivo Animal study

open access: yesInternational Journal of Hyperthermia, 2023
Purpose Surgical resection of the tendon is an effective treatment for severe contracture. Magnetic Resonance-guided Focused Ultrasound (MRgFUS) is a non-invasive ultrasonic therapy which produces a focal increase in temperature, subsequent tissue ...
William Chu Kwan   +5 more
doaj   +1 more source

Expression profiling of metalloproteinases and tissue inhibitors of metalloproteinases in normal and degenerate human achilles tendon [PDF]

open access: yes, 2006
To profile the messenger RNA (mRNA) expression for the 23 known genes of matrix metalloproteinases (MMPs), 19 genes of ADAMTS, 4 genes of tissue inhibitors of metalloproteinases (TIMPs), and ADAM genes 8, 10, 12, and 17 in normal, painful, and ruptured ...
Alfredson   +73 more
core   +1 more source

Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction

open access: yesAdvanced Healthcare Materials, EarlyView.
This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi   +13 more
wiley   +1 more source

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