FGF-2 enriched nanofiber scaffold for advancing achilles tendon healing: a comparative experimental investigation [PDF]
Frontiers in SurgeryIntroductionAchilles tendon rupture is a common and debilitating injury that significantly impacts mobility and quality of life. Effective treatment options that promote faster and more complete healing are needed.
Necmettin Turgut +6 more
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NEDD4 enhances bone‑tendon healing in rotator cuff tears by reducing fatty infiltration. [PDF]
Mol Med RepLi J, Peng Y, Zhen D, Guo C, Peng W.
europepmc +3 more sources
Dexamethasone treatment influences tendon healing through altered resolution and a direct effect on tendon cells [PDF]
Scientific ReportsInflammation, corticosteroids, and loading all affect tendon healing, with an interaction between them. However, underlying mechanisms behind the effect of corticosteroids and the interaction with loading remain unclear.
Franciele Dietrich-Zagonel +3 more
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Frontiers in Bioengineering and Biotechnology, 2023 At present, anterior cruciate ligament (ACL) reconstruction still has a high failure rate. Tendon graft and bone tunnel surface angiogenesis and bony ingrowth are the main physiological processes of tendon-bone healing, and also the main reasons for the ...
Bin Tian, Ming Zhang, Xin Kang
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In Vitro and In Vivo Effects of IGF-1 Delivery Strategies on Tendon Healing: A Review
International Journal of Molecular Sciences, 2023 Tendon injuries suffer from a slow healing, often ending up in fibrovascular scar formation, leading to inferior mechanical properties and even re-rupture upon resumption of daily work or sports.
Iris Miescher +3 more
semanticscholar +1 more source
Tendon tissue engineering: An overview of biologics to promote tendon healing and repair
Journal of Tissue Engineering, 2023 Tendons are dense connective tissues with a hierarchical polarized structure that respond to and adapt to the transmission of muscle contraction forces to the skeleton, enabling motion and maintaining posture.
Vera Citro +5 more
semanticscholar +1 more source
Current progress in growth factors and extracellular vesicles in tendon healing
International Wound Journal, 2023 Tendon injury healing is a complex process that involves the participation of a significant number of molecules and cells, including growth factors molecules in a key role.
Yufeng Wang, Jin Li
semanticscholar +1 more source
The effects of primary cilia-mediated mechanical stimulation on nestin<sup>+</sup>-BMSCs during bone-tendon healing. [PDF]
J Adv ResChen H +7 more
europepmc +2 more sources
PDGF-loaded microneedles promote tendon healing through p38/cyclin D1 pathway mediated angiogenesis
Materials Today Bio, 2022 Tendon injury is one of the most serious orthopedic diseases often leading to disability of patients. Major shortages of tendon healing are due to its multiple comorbidities, uncertainty of therapeutic efficacy and insufficient of angiogenesis.
Xuanzhe Liu +12 more
doaj +1 more source
Drug Delivery Approaches to Improve Tendon Healing
Tissue engineering. Part B, Reviews, 2023 Tendon injuries disrupt the transmission of forces from muscle to bone, leading to chronic pain, disability, and a large socioeconomic burden. Tendon injuries are prevalent; there are over 300,000 tendon repair procedures a year in the United States to ...
Emmanuela Adjei-Sowah +2 more
semanticscholar +1 more source