Results 1 to 10 of about 44,816 (214)
Journal of Functional Biomaterials, 2022 The tendon-to-bone interface is a special structure connecting the tendon and bone and is crucial for mechanical load transfer between dissimilar tissues.
Haihan Gao +11 more
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Transcriptomic Analysis of Tendon Healing Using an Extracellular Matrix-Coated, Polyurethane Scaffold [PDF]
BioengineeringLarge rotator cuff tendon injuries pose a dual clinical challenge: poor inherent healing capacity and high mechanical demands. To address this, we have developed a bifunctional scaffold that combines a slow-degrading, mechanically robust polyurethane ...
Ying Rao +6 more
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Reparative and Maladaptive Inflammation in Tendon Healing
Frontiers in Bioengineering and Biotechnology, 2021 Tendon injuries are common and debilitating, with non-regenerative healing often resulting in chronic disease. While there has been considerable progress in identifying the cellular and molecular regulators of tendon healing, the role of inflammation in ...
Varun Arvind +2 more
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Frontiers in Bioengineering and Biotechnology, 2023 At present, anterior cruciate ligament (ACL) reconstruction still has a high failure rate. Tendon graft and bone tunnel surface angiogenesis and bony ingrowth are the main physiological processes of tendon-bone healing, and also the main reasons for the ...
Bin Tian, Ming Zhang, Xin Kang
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PDGF-loaded microneedles promote tendon healing through p38/cyclin D1 pathway mediated angiogenesis
Materials Today Bio, 2022 Tendon injury is one of the most serious orthopedic diseases often leading to disability of patients. Major shortages of tendon healing are due to its multiple comorbidities, uncertainty of therapeutic efficacy and insufficient of angiogenesis.
Xuanzhe Liu +12 more
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Basic Research on Tendon Repair: Strategies, Evaluation, and Development
Frontiers in Medicine, 2021 Tendon is a fibro-elastic structure that links muscle and bone. Tendon injury can be divided into two types, chronic and acute. Each type of injury or degeneration can cause substantial pain and the loss of tendon function. The natural healing process of
Zhi Jie Li +5 more
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The Functions and Mechanisms of Tendon Stem/Progenitor Cells in Tendon Healing
Stem Cells International, 2023 Tendon injury is one of the prevalent disorders of the musculoskeletal system in orthopedics and is characterized by pain and limitation of joint function.
Jingwei Lu +8 more
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External stimulation: A potential therapeutic strategy for tendon-bone healing
Frontiers in Bioengineering and Biotechnology, 2023 Injuries at the tendon-bone interface are very common in the field of sports medicine, and healing at the tendon-bone interface is complex. Injuries to the tendon-bone interface can seriously affect a patient’s quality of life, so it is essential to ...
Shijie Fu +9 more
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Nihon Kikai Gakkai ronbunshu, 2023 A lack of the application of appropriate mechanical stimuli to cells within healing tissue in tendon defects has been proposed as a possible mechanism of incomplete defect healing with scar formation.
Eijiro MAEDA +3 more
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PLoS ONE, 2022 Tendons are composed of a heterogeneous cell environment, with Scleraxis-lineage (ScxLin) cells being the predominant population. Although ScxLin cells are required for maintenance of tendon homeostasis, their functions during tendon healing are unknown.
Antonion Korcari +4 more
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